Abstract：
Herein, we present the case of a 21-year-old man with a history of generalized tonic seizures since the age of 4 years. These seizures occurred either spontaneously or could be provoked by auditory stimuli such as the sounds of a vacuum cleaner or an electric shaver. Despite trials with 10 different anti-seizure medications, his seizures remained refractory. Interictal electroencephalography (EEG) revealed generalized epileptiform activity, whereas ictal EEG showed a generalized attenuation pattern. Magnetic resonance imaging revealed extensive chronic infarctions, predominantly in the bilateral cerebral watershed areas. At the age of 17, the patient underwent a one-stage complete callosotomy, which only achieved remission of auditory-provoked seizures. Based on this experience and published reports, we propose that the posterior corpus callosum, particularly the isthmus and anterior splenium, may be involved in seizures caused by unexpected sound stimuli.
摘要：
在这里，我们介绍了一例21岁男性患者,该患者自4岁起有全身性强直性癫痫发作史.这些癫痫发作是自发发生的，也可能是由听觉刺激引起的，例如真空吸尘器或电动剃须刀的声音。尽管使用了10种不同的抗癫痫药物进行了试验，他的癫痫发作仍然难治。发作间脑电图（EEG）显示全身性癫痫样活动，而发作脑电图显示出广义的衰减模式。磁共振成像显示广泛的慢性梗塞，主要在双侧大脑分水岭地区。在17岁时，患者接受了一期完整的call切开术，只能缓解听觉引起的癫痫发作。根据这些经验和发表的报告，我们建议后部胼胝体，特别是峡部和前脾，可能与意外声音刺激引起的癫痫发作有关。
