Abstract：
TwinsMX registry is a national research initiative in Mexico that aims to understand the complex interplay between genetics and environment in shaping physical and mental health traits among the country\'s population. With a multidisciplinary approach, TwinsMX aims to advance our knowledge of the genetic and environmental mechanisms underlying ethnic variations in complex traits and diseases, including behavioral, psychometric, anthropometric, metabolic, cardiovascular and mental disorders. With information gathered from over 2800 twins, this article updates the prevalence of several complex traits; and describes the advances and novel ideas we have implemented such as magnetic resonance imaging. The future expansion of the TwinsMX registry will enhance our comprehension of the intricate interplay between genetics and environment in shaping health and disease in the Mexican population. Overall, this report describes the progress in the building of a solid database that will allow the study of complex traits in the Mexican population, valuable not only for our consortium, but also for the worldwide scientific community, by providing new insights of understudied genetically admixed populations.
摘要：
TwinsMX注册是墨西哥的一项国家研究计划，旨在了解遗传与环境之间复杂的相互作用，以塑造该国人口的身心健康特征。通过多学科的方法，TwinsMX旨在提高我们对复杂特征和疾病中种族差异的遗传和环境机制的认识，包括行为，心理测量学,人体测量学,新陈代谢，心血管和精神障碍。从2800多名双胞胎那里收集到的信息，本文更新了几种复杂特征的普遍性；并描述了我们实施的进展和新颖的想法，例如磁共振成像。TwinsMX注册表的未来扩展将增强我们对遗传与环境之间在塑造墨西哥人口健康和疾病方面的复杂相互作用的理解。总的来说,这份报告描述了建立一个可靠数据库的进展，该数据库将允许研究墨西哥人口的复杂特征，不仅对我们的财团有价值，而且对于全世界的科学界来说，通过提供对未充分研究的基因混合人群的新见解。
