Health

Health
  • 文章类型: Journal Article
    目的:大专生的健康与学业成绩之间的关系可能对他们的大学经历和未来前景具有重要意义。然而,目前尚不存在对这种潜在联系的证据的全面总结。寻求填补这一空白,这项研究回顾了现存的关于大专生学业成绩和多个领域的健康状况的文献。
    方法:使用既定的方法论框架,我们进行了范围审查,以确定和总结2008年至2019年期间在美国进行的所有同行评审研究的属性,这些研究审查了大专生健康与学业成绩之间的关系.
    结果:搜索策略产生了12,488篇文章。重复数据删除后,初步筛选,并全面审查相关条款以确定资格,最终审查包括264篇文章。最常检查的健康领域是心理健康和物质使用。平均成绩(GPA)是最常见的学术指标。大多数研究都是在本科生中的单一机构进行的,一些研究集中在特定的学生亚群。几乎所有研究结果都表明,更健康的行为或最佳的健康状况与更好的学业成绩有关,或者不会对学术成功产生负面影响。
    结论:这项研究是了解现有研究范围的第一步,该研究检查了大专生的健康与学业成绩之间的联系。找到了大量的文献基础;然而,确定了几个差距,包括需要更多的队列研究,国家研究,研究生考试,并关注GPA以外的学术成果。
    OBJECTIVE: The relationship between postsecondary students\' health and academic outcomes may have important implications for their collegiate experience and their future prospects. Yet a comprehensive summary of the evidence examining this potential connection does not presently exist. Seeking to fill this gap, this study reviewed the extant literature on postsecondary students\' academic outcomes and health across multiple domains.
    METHODS: Using an established methodological framework, a scoping review was conducted to identify and summarize the attributes of all peer-reviewed research performed in the U.S. and published between 2008 and 2019 that examined the relationship between postsecondary students\' health and academic outcomes.
    RESULTS: The search strategy resulted in 12,488 articles. After deduplication, initial screening, and full review of relevant articles to determine eligibility, 264 articles were included in the final review. The most frequently examined health domains were mental health and substance use. Grade point average (GPA) was the most common academic measure investigated. Most studies took place at single institutions among undergraduate students, and several studies focused on specific student sub-populations. Almost all study results indicated that healthier behavior or optimal health status was associated with better academic outcomes or did not negatively impact academic success.
    CONCLUSIONS: This study serves as a first step in understanding the scope of existing research examining the connection between postsecondary students\' health and academic outcomes. A substantial literature base was found; however, several gaps were identified including the need for more cohort studies, national studies, examination of graduate students, and a focus on academic outcomes beyond GPA.
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  • 文章类型: Journal Article
    奶牛泌乳早期的特点是能量平衡(EB)之间复杂的相互作用,疾病,以及代谢和炎症状态的改变。这项研究的目的是根据泌乳早期的EB时间曲线对奶牛进行聚类,并研究EB聚类与炎症状态之间的关联。代谢状态,氧化应激,和疾病。选择Holstein-Friesian奶牛(n=153),并在哺乳期第1至6周进行疾病治疗监测。每周EB是根据哺乳期第1至6周的能量摄入和维持能量需求和产奶量计算的。每周分析血浆样本的第1至6周的代谢变量,以及泌乳第1、2和4周的炎症和氧化应激变量。肝脏活动指数(LAI)由血浆白蛋白计算,胆固醇,和视网膜结合蛋白浓度。首先,根据EB的时间曲线对奶牛进行聚类,产生4个簇(SP:稳定阳性;MN:轻度阴性;IN:中度阴性;SN:重度阴性)。SN簇中的奶牛具有较高的血浆非酯化脂肪酸和β-羟基丁酸酯浓度,与SP集群中的奶牛相比,MN和IN集群处于中间。SN簇中的奶牛具有较高的产奶量,与SP集群中的奶牛相比,第1周的干物质摄入量较低,胰岛素浓度较低,与SP和MN集群中的奶牛相比,葡萄糖和IGF-1浓度较低。能量平衡簇与血浆结合珠蛋白无关,胆固醇,白蛋白,对氧磷酶,和肝脏活动指数(LAI)。第二,根据健康状况对奶牛进行分组[IHP:接受炎症性健康问题治疗的奶牛(子宫内膜炎,发烧,临床乳腺炎,阴道分泌物或胎盘滞留);OHP:没有IHP但治疗其他健康问题的奶牛(牛奶热,囊性卵巢,爪子,和腿部问题,瘤胃和肠道问题或其他疾病);NHP:没有治疗的奶牛,分娩后的前6周]。健康状况组之间的能量平衡没有差异。与OHP相比,IHP奶牛的非酯化脂肪酸较低,血浆胰岛素浓度较高。IHP奶牛的血浆白蛋白浓度较低,与OHP和NHP相比,LAI较低,触珠蛋白浓度较高。总的来说,EB时间曲线与泌乳早期奶牛的代谢状态有关,但仅与炎症和氧化应激状态的标志物有限相关。炎症和代谢状态与泌乳早期的疾病事件有关,并对肝脏代谢造成长期影响。
    The early lactation period in dairy cows is characterized by complex interactions among energy balance (EB), disease, and alterations in metabolic and inflammatory status. The objective of this study was to cluster cows based on EB time profiles in early lactation and investigate the association between EB clusters and inflammatory status, metabolic status, oxidative stress, and disease. Holstein-Friesian dairy cows (n = 153) were selected and monitored for disease treatments during wk 1 to 6 in lactation. Weekly EB was calculated based on energy intake and energy requirements for maintenance and milk yield in wk 1 to 6 in lactation. Weekly plasma samples were analyzed for metabolic variables in wk 1 to 6, and inflammatory and oxidative stress variables in wk 1, 2, and 4 in lactation. Liver activity index (LAI) was computed from plasma albumin, cholesterol, and retino-binding protein concentration. First, cows were clustered based on time profiles of EB, resulting in 4 clusters (SP: stable positive; MN: mild negative; IN: intermediate negative; SN: severe negative). Cows in the SN cluster had higher plasma nonesterified fatty acids and β-hydroxybutyrate concentrations, compared with cows in the SP cluster, with the MN and IN cluster being intermediate. Cows in the SN cluster had a higher milk yield, lower dry matter intake in wk 1, lower insulin concentration compared with cows in the SP cluster, and lower glucose and IGF-1 concentration compared with cows in the SP and MN clusters. Energy balance clusters were not related with plasma haptoglobin, cholesterol, albumin, paraoxonase, and liver activity index (LAI). Second, cows were grouped based on health status [IHP: cows with treatment for inflammatory health problem (endometritis, fever, clinical mastitis, vaginal discharge or retained placenta); OHP: cows with no IHP but treatment for other health problem (milk fever, cystic ovaries, claw, and leg problems, rumen and intestine problems or other diseases); NHP: cows with no treatments, in the first 6 weeks after calving]. Energy balance was not different among health status groups. The IHP cows had lower nonesterified fatty acids and greater insulin concentration in plasma compared with OHP. The IHP cows had lower plasma albumin concentration, lower LAI and higher haptoglobin concentration compared with OHP and NHP. Overall, EB time profiles were associated with the metabolic status of dairy cows in early lactation, but were only limitedly related with markers of inflammation and oxidative stress status. Inflammatory and metabolic status were related to disease events in early lactation and caused prolonged effects on liver metabolism.
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  • 文章类型: Journal Article
    背景:全氟烷基和多氟烷基物质(PFAS)是一类广泛使用的人为化学物质。对其持久性和潜在不利影响的担忧导致了多个二级研究出版物。这里,我们的目标是通过检查研究差距来评估系统二级文献中的证据基础,评估评论的质量,探索跨学科的联系。
    方法:本研究采用了系统的证据映射方法来评估有关生物学,环境,以及暴露于35种氟化化合物的医学方面。纳入标准包括发表在同行评审期刊上的系统评价,预打印,和论文。跨电子数据库和灰色文献的综合搜索确定了相关评论。数据提取和综合涉及映射文献内容和叙事描述。我们采用了AMSTAR2清单的修改版本来评估评论的方法学严谨。文献计量数据分析揭示了学术文献中的模式和趋势。该研究的研究方案先前已预先注册(osf.io/2tpn8)并已发布(Vendl等人。,环境国际158(2022)106973)。该数据库可通过https://hi-this-is-lorenzo上的此系统证据图的交互式和用户友好的Web应用程序免费访问。shinyapps.io/PFAS_SEM_Shiny_App/。
    结果:我们的地图包括总共175个系统综述。多年来,每年的出版物数量稳步增加,2021年出现显著飙升。大多数评论都集中在人类暴露上,而与环境和动物相关的综述较少,并且通常缺乏严格的系统文献检索和筛选方法。审查结果主要与人类健康相关,特别是与生殖和儿童的发育健康。动物评论主要集中在受控实验室环境中进行的研究,野生动物评论的特点是鸟类和鱼类物种的过度代表。最近的评论越来越多地纳入了定量综合方法。审查的方法优势包括对研究选择过程的详细描述和潜在利益冲突的披露。然而,在报告方法中严重缺乏细节方面观察到弱点。文献计量分析显示,最有生产力的作者在自己的国家进行合作,导致有限和集群的国际合作。
    结论:在对现有系统二级文献的概述中,我们绘制文献内容,评估评论的方法论质量,突出数据差距,并绘制研究网络集群。我们的目标是促进文献综述,指导未来的研究计划,并增加跨国合作的机会。此外,我们讨论了这个系统的证据图及其公开的数据库如何使科学家受益,监管机构,和其他利益相关者,通过提供有关PFAS暴露的当前系统二级文献。
    BACKGROUND: Per- and polyfluoroalkyl substances (PFAS) are a class of widely used anthropogenic chemicals. Concerns regarding their persistence and potential adverse effects have led to multiple secondary research publications. Here, we aim to assess the resulting evidence base in the systematic secondary literature by examining research gaps, evaluating the quality of reviews, and exploring interdisciplinary connections.
    METHODS: This study employed a systematic evidence-mapping approach to assess the secondary literature on the biological, environmental, and medical aspects of exposure to 35 fluorinated compounds. The inclusion criteria encompassed systematic reviews published in peer-reviewed journals, pre-prints, and theses. Comprehensive searches across electronic databases and grey literature identified relevant reviews. Data extraction and synthesis involved mapping literature content and narrative descriptions. We employed a modified version of the AMSTAR2 checklist to evaluate the methodological rigour of the reviews. A bibliometric data analysis uncovered patterns and trends in the academic literature. A research protocol for this study was previously pre-registered (osf.io/2tpn8) and published (Vendl et al., Environment International 158 (2022) 106973). The database is freely accessible through the interactive and user-friendly web application of this systematic evidence map at https://hi-this-is-lorenzo.shinyapps.io/PFAS_SEM_Shiny_App/.
    RESULTS: Our map includes a total of 175 systematic reviews. Over the years, there has been a steady increase in the annual number of publications, with a notable surge in 2021. Most reviews focused on human exposure, whereas environmental and animal-related reviews were fewer and often lacked a rigorous systematic approach to literature search and screening. Review outcomes were predominantly associated with human health, particularly with reproductive and children\'s developmental health. Animal reviews primarily focused on studies conducted in controlled laboratory settings, and wildlife reviews were characterised by an over-representation of birds and fish species. Recent reviews increasingly incorporated quantitative synthesis methodologies. The methodological strengths of the reviews included detailed descriptions of study selection processes and disclosure of potential conflicts of interest. However, weaknesses were observed in the critical lack of detail in reporting methods. A bibliometric analysis revealed that the most productive authors collaborate within their own country, leading to limited and clustered international collaborations.
    CONCLUSIONS: In this overview of the available systematic secondary literature, we map literature content, assess reviews\' methodological quality, highlight data gaps, and draw research network clusters. We aim to facilitate literature reviews, guide future research initiatives, and enhance opportunities for cross-country collaboration. Furthermore, we discuss how this systematic evidence map and its publicly available database benefit scientists, regulatory agencies, and other stakeholders by providing access to current systematic secondary literature on PFAS exposure.
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  • 文章类型: Editorial
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  • 文章类型: Journal Article
    患者不愿使用远程医疗健康服务,与其替代的面对面访问相比。一个原因是,只有在产品被采用和体验后,远程医疗才能被准确评估并与其替代品进行比较。因此,增加第一次经历的可能性的干预可以产生持久的影响。本文报告了与健康保险公司合作进行的随机现场实验的结果。在干预期间,样本中的3,469个家庭中有一半收到了定期电子邮件,其中包含有关可用服务的信息。它有效地增加了对远程医疗的接受和需求。在实验的前8个月里,分配到治疗组的患者使用该服务至少1次的可能性高出6个百分点(与对照组相比,使用远程医疗的几率约为5倍).干预开始八个月后,治疗组的虚拟咨询数量是对照组的六倍。这些结果,即使受到干预发生的样本和背景的限制,提供更多证据,说明信息干预措施如何增加卫生部门的技术接受,并可作为评估远程医疗对健康结果的因果关系影响的垫脚石.
    Patients are reluctant to use telemedicine health services, compared to its substitute in-person visits. One reason is that telemedicine can be accurately evaluated and compared to its substitute only after the product has been adopted and experienced. As such, an intervention that increases the probability of a first experience can have lasting effects. This article reports the results of a randomized field experiment conducted in collaboration with a health insurance company. During the intervention, half of the households out of 3,469 in the sample received periodic e-mails with information about the available services. It effectively increased the take-up and demand for telemedicine. Within the first 8 months of the experiment, patients assigned to the treatment group were 6 percentage points more likely to have used the service at least once (and had about five times the odds of using telemedicine compared to those in the control group). Eight months after the start of the intervention, the number of virtual consultations by the treatment group was six times larger than that of the control group. These results, even if limited by the sample and context in which the intervention took place, provide additional evidence about how information interventions can increase technological take-up within the health sector and could serve as the stepping stone for evaluating the impact of telemedicine on health outcomes causally.
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  • 文章类型: Journal Article
    背景:吸烟对全世界的死亡率有显著的贡献,特别是在非传染性和可预防的疾病,如心血管疾病,呼吸状况,中风,还有肺癌.这项研究旨在分析吸烟对全球死亡的影响。及其与主要收入群体死亡率的关系。
    方法:从1990年到2019年,综合分析涵盖了199个国家和地区。该研究将国家分为四个收入组:高收入,中高收入,中等偏下收入,和低收入。
    结果:研究结果强调了全球吸烟对死亡率的深远影响。值得注意的是,心血管疾病死亡率在中高收入和高收入人群中都受到显著影响.慢性呼吸系统疾病死亡率对所有收入群体都有重大影响。此外,卒中相关死亡率在中低端地区观察到,中上,高收入群体。这些结果突出了吸烟率对全球死亡率的普遍影响。影响各个社会经济层面的个人。
    结论:该研究强调了吸烟对死亡率的重要影响,特别是在高收入国家。它强调了在这些地区采取有针对性的干预措施的紧迫性,以应对吸烟对公共卫生带来的具体挑战。政策建议包括实施禁止性措施,扩大到室内公共区域,如工作场所和公共交通服务。此外,拨款用于烟草和健康研究,必须确保政策制定者始终如一地了解这一复杂领域的新兴事实和趋势。
    BACKGROUND: Smoking significantly contributes to the mortality rates worldwide, particularly in non-communicable and preventable diseases such as cardiovascular ailments, respiratory conditions, stroke, and lung cancer. This study aims to analyse the impact of smoking on global deaths, and its association with mortality across the main income groups.
    METHODS: The comprehensive analysis spans 199 countries and territories from 1990 to 2019. The study categorises countries into four income groups: high income, upper middle income, lower middle income, and low income.
    RESULTS: The findings underscore the profound impact of global tobacco smoking on mortality. Notably, cardiovascular disease mortality is notably affected in both upper-middle-income and high-income groups. Chronic respiratory disease mortality rates show a significant impact across all income groups. Moreover, stroke-related mortality is observed in the lower-middle, upper-middle, and high-income groups. These results highlight the pervasive influence of smoking prevalence on global mortality, affecting individuals across various socioeconomic levels.
    CONCLUSIONS: The study underscores the critical implications of smoking on mortality rates, particularly in high-income countries. It emphasises the urgency of targeted interventions in these regions to address the specific challenges posed by tobacco smoking on public health. Policy recommendations include implementing prohibitive measures extending to indoor public areas such as workplaces and public transportation services. Furthermore, allocating funds for research on tobacco and health, is imperative to ensure policymakers are consistently informed about emerging facts and trends in this complex domain.
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  • 文章类型: Journal Article
    许多研究已经确定了健康指标的宗教相关性,但在以色列或侨民的犹太人口中进行的活动相对较少。这项研究调查了在以色列熟悉的犹太宗教身份和遵守类别中身心健康和福祉的宗教梯度的可能性:hiloni(世俗),Masortilodati(传统,非宗教),Masorti(传统),dati(宗教或东正教),和charedi(超正统)。数据来自18岁及以上的犹太受访者(N=2916),来自以色列的新样本,22个国家的全球繁荣研究,使用分层,基于概率的抽样和人口统计评估,社会经济,政治,宗教,健康相关,和其他变量。这项分析调查了以色列犹太人在9个身心健康和福祉指标上的宗教差异。使用单向ANOVA和ANCOVA的策略,针对复杂的采样设计组件进行调整,在八个结果测量中发现了统计学上显著的“剂量反应”样梯度,通过额外的多次比较测试验证。对于四个“积极”措辞的指标(身心健康,幸福,和生活满意度),从hiloni到charedi类别的分数一直在增加。对于五个“负面”措辞指标中的四个(身体疼痛,抑郁症,焦虑,和痛苦),相同类别的分数下降。结果经受住了年龄影响的调整,性别,教育,婚姻状况,城市化,收入,和诞生(无论出生在以色列)。在以色列犹太人中,更大的宗教信仰与更高水平的健康和福祉以及更低水平的躯体和心理困扰有关。
    Numerous studies have identified religious correlates of health indicators, but relatively few have been conducted among Jewish populations in Israel or the diaspora. This study investigates the possibility of a religious gradient in physical and mental health and well-being across the familiar categories of Jewish religious identity and observance in Israel: hiloni (secular), masorti lo dati (traditional, non-religious), masorti (traditional), dati (religious or Orthodox), and charedi (ultra-Orthodox). Data are from Jewish respondents aged 18 and over (N = 2916) from the Israeli sample of the new, 22-nation Global Flourishing Study, which used stratified, probability-based sampling and assessed demographic, socioeconomic, political, religious, health-related, and other variables. This analysis investigated religious differences in nine indicators of physical and mental health and well-being among Israeli Jews. Using a strategy of one-way ANOVA and ANCOVA, adjusting for complex sampling design components, a statistically significant \"dose-response\"-like gradient was found for eight of the outcome measures, validated by additional multiple comparison tests. For four \"positively\" worded indicators (physical and mental health, happiness, and life satisfaction), scores increased consistently from the hiloni to the charedi categories. For four of five \"negatively\" worded indicators (bodily pain, depression, anxiety, and suffering), scores decreased across the same categories. Results withstood adjusting for effects of age, sex, education, marital status, urbanicity, income, and nativity (whether born in Israel). Among Israeli Jews, greater religiousness was associated with higher levels of health and well-being and lower levels of somatic and psychological distress.
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  • 文章类型: English Abstract
    As an important force in promoting the transformation and upgrading of the national economy, the occupational health of the Internet industry\'s employees has received widespread attention. This paper examines the current situation of occupational health risks and management in the Internet industry at home and abroad, and on this basis reveals the physical and mental health problems of Internet industry employees. Combining the existing regulations, policies and standard documents at home and abroad, countermeasures are proposed to improve the relevant laws and regulations and their guidelines, implement relevant job design requirements, build a healthy working environment, optimise the work management system and carry out workplace health promotion, in order to provide ideas to accelerate the improvement of occupational health issues in the Internet industry.
    互联网行业作为推动经济转型升级的重要力量,其从业人员的职业健康问题受到广泛关注。本文研究了国内外有关互联网行业职业健康风险及管理现状,在此基础上分析了互联网行业从业人员生理、心理健康问题。结合现有法规政策及标准文件,就完善相关法律法规及其指南、落实相关作业设计要求、建设健康工作环境、优化作业管理制度、开展工作场所健康促进等提出对策建议,为加快推进改善互联网行业职业健康问题提供思路。.
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  • 文章类型: Editorial
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  • 文章类型: Journal Article
    背景:尽管关于动物饲养操作(AFO)包括集中动物饲养操作(CAFO)的文献越来越多,关于不成比例的暴露和相关健康负担的研究相对有限,并且没有定论。
    目的:我们系统回顾了以前关于AFOs/CAFOs的文献,专注于暴露评估,相关的健康结果,以及与环境正义(EJ)和潜在弱势群体相关的变量。
    方法:我们对数据库(MEDLINE/PubMed和WebofScience)进行了系统搜索,并进行了引文筛选。标题筛选,摘要,全文文章和数据提取由成对的审稿人独立进行。我们总结了每项研究的信息(即,研究地点,学习期间,研究人群,研究类型,研究设计,统计方法,和调整后的变量(如果检查了健康关联),和主要发现),AFO/CAFO特性和暴露评估(即,动物类型,数据源,暴露量,和暴露评估),健康结果或症状(如果检查了健康关联),以及与EJ和潜在脆弱人群相关的信息(与暴露和/或健康关联有关,考虑到弱势群体,相关变量,以及与EJ和弱势群体相关的主要发现)。
    结果:经过10,963篇论文的初步筛选,我们确定了76项符合条件的研究.这篇综述发现,相对较少数量的研究(20项研究)调查了与AFOs/CAFOs暴露和/或相关健康结果相关的EJ和脆弱性问题(例如,呼吸道疾病/症状,感染)。我们发现了不同研究结果的差异,人口,这些指标用于AFO/CAFO暴露评估,以及与EJ和漏洞相关的变量。AFO/CAFO暴露评估最常用的指标是设施或动物的存在或接近。与差异有关的调查最多的变量是种族/民族和社会经济地位。
    结论:本综述的研究结果提供了暗示性证据,表明与AFO/CAFO暴露相关的一些暴露和/或健康反应较高的亚群存在差异,尽管研究结果各不相同。
    BACKGROUND: Despite growing literature on animal feeding operations (AFOs) including concentrated animal feeding operations (CAFOs), research on disproportionate exposure and associated health burden is relatively limited and shows inconclusive findings.
    OBJECTIVE: We systematically reviewed previous literature on AFOs/CAFOs, focusing on exposure assessment, associated health outcomes, and variables related to environmental justice (EJ) and potentially vulnerable populations.
    METHODS: We conducted a systematic search of databases (MEDLINE/PubMed and Web of Science) and performed citation screening. Screening of titles, abstracts, and full-text articles and data extraction were performed independently by pairs of reviewers. We summarized information for each study (i.e., study location, study period, study population, study type, study design, statistical methods, and adjusted variables (if health association was examined), and main findings), AFO/CAFO characteristics and exposure assessment (i.e., animal type, data source, measure of exposure, and exposure assessment), health outcomes or symptoms (if health association was examined), and information related to EJ and potentially vulnerable populations (in relation to exposure and/or health associations, vulnerable populations considered, related variables, and main findings in relation to EJ and vulnerable populations).
    RESULTS: After initial screening of 10,963 papers, we identified 76 eligible studies. This review found that a relatively small number of studies (20 studies) investigated EJ and vulnerability issues related to AFOs/CAFOs exposure and/or associated health outcomes (e.g., respiratory diseases/symptoms, infections). We found differences in findings across studies, populations, the metrics were used for AFO/CAFO exposure assessment, and variables related to EJ and vulnerability. The most commonly used metric for AFO/CAFO exposure assessment was presence of or proximity to facilities or animals. The most investigated variables related to disparities were race/ethnicity and socioeconomic status.
    CONCLUSIONS: Findings from this review provide suggestive evidence that disparities exist with some subpopulations having higher exposure and/or health response in relation to AFO/CAFO exposure, although results varied across studies.
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