Abstract：
This study aims to investigate the brain networks engaged in the comprehension of indirect language, as well as the individual difference in this capacity. Specially, we aim to determine whether the difference is solely influenced by the difference in individuals\' default network (DN)/language network or whether it also relies on the networks associated with processing of complex cognitive tasks, particularly the multiple demand network (MDN). Conversational indirectness scale (CIS) scores in the interpretation dimension were used as a behavioral indicator of the indirect comprehension tendency. Reading time difference between indirect replies and direct replies collected through a self-paced reading experiment was deemed as a behavioral indicator of comprehension speed of indirect replies comprehension. The two behavioral indicators were combined with resting-state functional magnetic resonance imaging (rs-fMRI). The behaviour-rfMRI analysis showed that ALFF value of right SPL and the functional connectivity (FC) between the right SPL and right IPL/SMA/ITG/Precuneus/bilateral IFG were positively correlated with the interpretation dimension of CIS scores. In addition, the ALFF value of right fusiform gyrus, the FC between the right fusiform gyrus and right precuneus, and the FCs between right SPL and right IPL/Precuneus/IFG were negatively correlated with indirect replies comprehension speed. Overlapping of these regions with large-scale brain network revealed that the right SPL was mainly located in the MDN, and the right fusiform gyrus was mainly located in the language network. Additionally, the areas showing functional connectivity with these regions were primarily located in the MDN, with a smaller subset located in the DN. Our findings suggest that the ability of individuals to actively and rapidly acquire indirect meaning relies not only on the support of the DN and the language network, but also requires collective support from the MDN.
摘要：
本研究旨在调查参与理解间接语言的大脑网络，以及这种能力的个体差异。特别是,我们的目标是确定这种差异是否仅受到个人默认网络（DN）/语言网络差异的影响，或者它是否也依赖于与复杂认知任务处理相关的网络，特别是多需求网络(MDN)。解释维度中的会话间接性量表（CIS）得分被用作间接理解倾向的行为指标。通过自定进度的阅读实验收集的间接答复和直接答复之间的阅读时间差被认为是间接答复理解速度的行为指标。将两种行为指标与静息态功能磁共振成像（rs-fMRI）结合。行为-rfMRI分析表明，右SPL的ALFF值以及右SPL与右IPL/SMA/ITG/Precuneus/双侧IFG之间的功能连接（FC）与CIS评分的解释维度呈正相关。此外,右梭状回的ALFF值，右梭状回和右前肌之间的FC，右SPL和右IPL/Precuneus/IFG之间的FC与间接答复理解速度呈负相关。这些区域与大规模脑网络的重叠表明，正确的SPL主要位于MDN中，右梭状回主要位于语言网络中。此外,与这些区域显示功能连接的区域主要位于MDN，具有位于DN中的较小的子集。我们的研究结果表明，个人积极和快速获得间接意义的能力不仅依赖于DN和语言网络的支持，但也需要MDN的集体支持。
