关键词: Brain death Cerebral blood flow Color Doppler ultrasound Ophthalmic Artery Ultrasonography

Mesh : Humans Brain Death / diagnostic imaging diagnosis Male Female Middle Aged Single-Blind Method Adult Prospective Studies Ultrasonography, Doppler, Transcranial / methods Aged Computed Tomography Angiography / methods Young Adult Ophthalmic Artery / diagnostic imaging Sensitivity and Specificity Cerebrovascular Circulation / physiology Adolescent Orbit / diagnostic imaging blood supply

来  源:   DOI:10.1016/j.clineuro.2024.108289

Abstract:
Transcranial Doppler ultrasound (TDUS), computed tomography angiography (CTA), and transcranial Doppler ultrasound to detect cerebral blood flow are among the adjunctive tests in diagnosing brain death. This study aimed to investigate the effectiveness of orbital doppler ultrasound (ODUS).
This prospective, single-blind study included 66 patients for whom brain death was to be diagnosed. Primary outcome measures were ODUS measurements, Ophthalmic artery peak systolic velocity (PSV), end-diastolic velocity (EDV), and resistive indices (RI) measurements recorded during the brain death determination process. Secondary outcome measures were computed tomography angio (CTA), transcranial Doppler ultrasound (TDUS), and demographic data.
This study investigating the effectiveness of ODUS in diagnosing brain death provided diagnostic success with 100% sensitivity and 93% specificity compared to CT angiography. It was noted that anatomical variations may limit its use.
ODUS was found to have high sensitivity and specificity in the diagnosis of clinical brain death. It may assist in early prognostic assessment and shorten patient follow-up and diagnostic processes.
摘要:
目的:经颅多普勒超声(TDUS),计算机断层扫描血管造影(CTA),和经颅多普勒超声检测脑血流是诊断脑死亡的辅助检查之一。本研究旨在探讨眼眶多普勒超声(ODUS)的有效性。
方法:这种前瞻性,单盲研究纳入了66例需诊断为脑死亡的患者.主要结局指标是ODUS测量,眼动脉收缩期峰值流速(PSV),舒张末期血流速度(EDV),和在脑死亡确定过程中记录的电阻指数(RI)测量值。次要结果指标是血管CT(CTA),经颅多普勒超声(TDUS),和人口统计数据。
结果:这项研究调查了ODUS在诊断脑死亡中的有效性,与CT血管造影相比,以100%的灵敏度和93%的特异性提供了诊断成功。注意到解剖变化可能限制其使用。
结论:ODUS在临床脑死亡诊断中具有较高的敏感性和特异性。它可能有助于早期预后评估并缩短患者随访和诊断过程。
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