This prospective, single-blind study included 66 patients for whom brain death was to be diagnosed. Primary outcome measures were ODUS measurements, Ophthalmic artery peak systolic velocity (PSV), end-diastolic velocity (EDV), and resistive indices (RI) measurements recorded during the brain death determination process. Secondary outcome measures were computed tomography angio (CTA), transcranial Doppler ultrasound (TDUS), and demographic data.
This study investigating the effectiveness of ODUS in diagnosing brain death provided diagnostic success with 100% sensitivity and 93% specificity compared to CT angiography. It was noted that anatomical variations may limit its use.
ODUS was found to have high sensitivity and specificity in the diagnosis of clinical brain death. It may assist in early prognostic assessment and shorten patient follow-up and diagnostic processes.
方法:这种前瞻性,单盲研究纳入了66例需诊断为脑死亡的患者.主要结局指标是ODUS测量,眼动脉收缩期峰值流速(PSV),舒张末期血流速度(EDV),和在脑死亡确定过程中记录的电阻指数(RI)测量值。次要结果指标是血管CT(CTA),经颅多普勒超声(TDUS),和人口统计数据。
结果:这项研究调查了ODUS在诊断脑死亡中的有效性,与CT血管造影相比,以100%的灵敏度和93%的特异性提供了诊断成功。注意到解剖变化可能限制其使用。
结论:ODUS在临床脑死亡诊断中具有较高的敏感性和特异性。它可能有助于早期预后评估并缩短患者随访和诊断过程。