METHODS: We retrospectively reviewed 2206 pediatric patients who had received an allo-HSCT between January 2013 and December 2019 at the Hebei Yanda Lu Daopei Hospital, and analyzed the role of ALS in prognosis following HSCT.
RESULTS: In our research, ALS was divided into two categories: 15 cases of bronchiolitis obliterans syndrome (BOS) and 13 cases of idiopathic pneumonia syndrome (IPS). Following treatment of the ALS, 18 patients survived (18/28, 64.3%), and 10 patients died of respiratory failure or infection (10/28, 35.7%).
CONCLUSIONS: The OS of ALS in Hebei Yanda Lu Daopei Hospital is significantly higher than others, and they were cited to be related to early diagnosis and timely FAM treatment in previous reports.
方法:我们回顾性分析了2013年1月至2019年12月在河北燕达陆道培医院接受allo-HSCT的2206例儿科患者。分析ALS在HSCT预后中的作用。
结果:在我们的研究中,ALS分为两大类:闭塞性细支气管炎综合征(BOS)15例和特发性肺炎综合征(IPS)13例。ALS治疗后,18例患者存活(18/28,64.3%),10例患者死于呼吸衰竭或感染(10/28,35.7%)。
结论:河北燕达陆道培医院ALS的OS明显高于其他患者,在以前的报道中,它们被认为与早期诊断和及时FAM治疗有关。