PDF(Pubmed)
Abstract：
This systematic review aims to analyze the effects of acute and chronic exercise on appetite and appetite regulation in patients with abnormal glycemic control. PubMed, Web of Science, and the Cochrane Central Register of Controlled Trials were searched for eligible studies. The included studies had to report assessments of appetite (primary outcome). Levels of appetite-regulating hormones were analyzed as secondary outcomes (considered, if additionally reported). Seven studies with a total number of 211 patients with prediabetes or type 2 diabetes mellitus (T2DM) met the inclusion criteria. Ratings of hunger, satiety, fullness, prospective food consumption, nausea, and desire to eat, as well as levels of (des-)acylated ghrelin, glucagon-like peptide 1, glucose-dependent insulinotropic peptide, pancreatic polypeptide, peptide tyrosine tyrosine, leptin, and spexin were considered. Following acute exercise, the effects on appetite (measured up to one day post-exercise) varied, while there were either no changes or a decrease in appetite ratings following chronic exercise, both compared to control conditions (without exercise). These results were accompanied by inconsistent changes in appetite-regulating hormone levels. The overall risk of bias was low. The present results provide more evidence for an appetite-reducing rather than an appetite-increasing effect of (chronic) exercise on patients with prediabetes or T2DM. PROSPERO ID: CRD42023459322.
摘要：
本系统评价旨在分析急性和慢性运动对血糖控制异常患者食欲和食欲调节的影响。PubMed,WebofScience,并在Cochrane中央对照试验登记册中搜索了符合条件的研究.纳入的研究必须报告食欲评估（主要结果）。食欲调节激素水平作为次要结果进行分析（考虑，如果另外报告)。七项研究，总共211名糖尿病前期或2型糖尿病（T2DM）患者符合纳入标准。饥饿程度,饱腹感,丰满度,预期的食物消费，恶心,渴望吃，以及（脱）酰化生长素释放肽的水平，胰高血糖素样肽1，葡萄糖依赖性促胰岛素分泌肽，胰多肽,肽酪氨酸酪氨酸，瘦素,和spexin被考虑。急性运动后,对食欲的影响(在运动后一天内测量)各不相同，虽然长期运动后食欲没有变化或下降，两者都与控制条件(没有运动)相比。这些结果伴随着食欲调节激素水平的不一致变化。总体偏倚风险较低。目前的结果提供了更多的证据，证明（慢性）运动对糖尿病前期或T2DM患者的食欲降低而不是食欲增加的作用。PROSPEROID:CRD42023459322。
