关键词: Crimean-Congo hemorrhagic fever bunyavirus countermeasure treatment vaccine vector-borne infections viral hemorrhagic fever viruses

Mesh : Hemorrhagic Fever, Crimean / epidemiology prevention & control transmission diagnosis virology Humans Hemorrhagic Fever Virus, Crimean-Congo / genetics Animals Ticks / virology

来  源:   DOI:10.3201/eid3005.231647   PDF(Pubmed)

Abstract:
Crimean-Congo hemorrhagic fever (CCHF) is a tickborne infection that can range from asymptomatic to fatal and has been described in >30 countries. Early identification and isolation of patients with suspected or confirmed CCHF and the use of appropriate prevention and control measures are essential for preventing human-to-human transmission. Here, we provide an overview of the epidemiology, clinical features, and prevention and control of CCHF. CCHF poses a continued public health threat given its wide geographic distribution, potential to spread to new regions, propensity for genetic variability, and potential for severe and fatal illness, in addition to the limited medical countermeasures for prophylaxis and treatment. A high index of suspicion, comprehensive travel and epidemiologic history, and clinical evaluation are essential for prompt diagnosis. Infection control measures can be effective in reducing the risk for transmission but require correct and consistent application.
摘要:
克里米亚-刚果出血热(CCHF)是一种从无症状到致命的蜱传感染,已在30多个国家进行了描述。早期识别和隔离疑似或确诊的CCHF患者,并采取适当的预防和控制措施,对于防止人与人之间的传播至关重要。这里,我们提供了流行病学的概述,临床特征,以及CCHF的预防和控制。鉴于其广泛的地理分布,CCHF构成了持续的公共卫生威胁,有可能传播到新的地区,遗传变异倾向,以及严重和致命疾病的可能性,除了有限的预防和治疗医学对策。高度怀疑,全面的旅行和流行病学史,和临床评估对于及时诊断至关重要。感染控制措施可以有效降低传播风险,但需要正确和一致的应用。
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