PDF(Pubmed)
Abstract：
BACKGROUND: Adolescence is characterized by complex and dynamic changes, often involving experimentation, including the use of psychotropic substances. Although it is well-established that recreational psychotropic drugs are associated with suicide ideation in adults, evidence of this association in adolescents remains limited.
OBJECTIVE: To investigate the relationship between suicide ideation and psychotropic recreational drug use among adolescents.
METHODS: Systematic review with meta-analysis developed at Universidade Federal de Uberlândia (UFU) and Universidade Estadual de Campinas (UNICAMP), Brazil.
METHODS: A search across eight electronic databases for observational studies, without language or publication year restrictions, was conducted. The Joanna Briggs Institute tool was used to assess the risk of bias. Random-effects meta-analyses and odds ratios were used to measure the effects.
RESULTS: The search yielded 19,732 studies, of which 78 were included in the qualitative synthesis and 32 in the meta-analysis. The findings indicated that suicidal ideation was 1.96 times more likely (95% confidence interval, CI = 1.47; 2.61) for adolescents who used some drug recurrently and 3.32 times more likely (95%CI = 1.86; 5.93) among those who abused drugs. Additionally, adolescents who used cannabis were 1.57 times more likely (95%CI = 1.34; 1.84) to experience suicide ideation compared with non-users, while cocaine users had 2.57 times higher odds (95%CI = 1.47; 4.50).
CONCLUSIONS: Psychotropic recreational drug use is associated with suicidal ideation among adolescents regardless of current or previous use, abuse, or type of substance used.
BACKGROUND: Registered in the PROSPERO database under the identification number CRD42021232360. https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021232360.
OBJECTIVE: To investigate the relationship between suicide ideation and psychotropic recreational drug use among adolescents.
METHODS: Systematic review with meta-analysis developed at Universidade Federal de Uberlândia (UFU) and Universidade Estadual de Campinas (UNICAMP), Brazil.
METHODS: A search across eight electronic databases for observational studies, without language or publication year restrictions, was conducted. The Joanna Briggs Institute tool was used to assess the risk of bias. Random-effects meta-analyses and odds ratios were used to measure the effects.
RESULTS: The search yielded 19,732 studies, of which 78 were included in the qualitative synthesis and 32 in the meta-analysis. The findings indicated that suicidal ideation was 1.96 times more likely (95% confidence interval, CI = 1.47; 2.61) for adolescents who used some drug recurrently and 3.32 times more likely (95%CI = 1.86; 5.93) among those who abused drugs. Additionally, adolescents who used cannabis were 1.57 times more likely (95%CI = 1.34; 1.84) to experience suicide ideation compared with non-users, while cocaine users had 2.57 times higher odds (95%CI = 1.47; 4.50).
CONCLUSIONS: Psychotropic recreational drug use is associated with suicidal ideation among adolescents regardless of current or previous use, abuse, or type of substance used.
BACKGROUND: Registered in the PROSPERO database under the identification number CRD42021232360. https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021232360.
摘要：
背景：青少年的特征是复杂而动态的变化，经常涉及实验，包括使用精神药物。尽管公认的是，娱乐性精神药物与成年人的自杀观念有关，在青少年中这种关联的证据仍然有限.
目的：探讨青少年自杀意念与精神药物使用的关系。
方法：在乌伯兰联邦大学（UFU）和坎皮纳斯大学（UNICAMP）开发的荟萃分析的系统评价，巴西。
方法：在八个电子数据库中搜索观察性研究，没有语言或出版年份限制，进行了。乔安娜·布里格斯研究所的工具被用来评估偏见的风险。随机效应荟萃分析和优势比用于衡量效果。
结果：搜索产生了19,732项研究，其中78项纳入定性综合,32项纳入荟萃分析.结果表明，自杀意念的可能性是1.96倍(95%置信区间，CI=1.47;2.61）适用于反复使用某些药物的青少年，滥用药物的可能性是其3.32倍（95CI=1.86;5.93）。此外,与非吸食者相比，吸食大麻的青少年出现自杀意念的可能性是其1.57倍（95CI=1.34;1.84），而可卡因使用者的赔率高2.57倍（95CI=1.47；4.50）。
结论：在青少年中，无论目前或以前使用什么，使用精神药物都与自杀意念有关。滥用,或使用的物质类型。
背景：在PROSPERO数据库中注册的标识号为CRD42021232360。https://www.crd.约克。AC.uk/prospro/display_record.php?ID=CRD42021232360。
目的：探讨青少年自杀意念与精神药物使用的关系。
方法：在乌伯兰联邦大学（UFU）和坎皮纳斯大学（UNICAMP）开发的荟萃分析的系统评价，巴西。
方法：在八个电子数据库中搜索观察性研究，没有语言或出版年份限制，进行了。乔安娜·布里格斯研究所的工具被用来评估偏见的风险。随机效应荟萃分析和优势比用于衡量效果。
结果：搜索产生了19,732项研究，其中78项纳入定性综合,32项纳入荟萃分析.结果表明，自杀意念的可能性是1.96倍(95%置信区间，CI=1.47;2.61）适用于反复使用某些药物的青少年，滥用药物的可能性是其3.32倍（95CI=1.86;5.93）。此外,与非吸食者相比，吸食大麻的青少年出现自杀意念的可能性是其1.57倍（95CI=1.34;1.84），而可卡因使用者的赔率高2.57倍（95CI=1.47；4.50）。
结论：在青少年中，无论目前或以前使用什么，使用精神药物都与自杀意念有关。滥用,或使用的物质类型。
背景：在PROSPERO数据库中注册的标识号为CRD42021232360。https://www.crd.约克。AC.uk/prospro/display_record.php?ID=CRD42021232360。
