%0 Systematic Review
%T Suicide ideation and psychotropic recreational drug use by adolescents: a systematic review and meta-analysis.
%A Oliveira Gracini CL
%A Nascimento GG
%A Vidigal MTC
%A Oliveira MN
%A Herval ÁM
%A Blumenberg C
%A Vieira WA
%A Lima RR
%A Paranhos LR
%J Sao Paulo Med J
%V 142
%N 4
%D 2024
%M 38655989
%F 1.838
%R 10.1590/1516-3180.2022.0641.R2.23012024
%X <B>BACKGROUND: </B>Adolescence is characterized by complex and dynamic changes, often involving experimentation, including the use of psychotropic substances. Although it is well-established that recreational psychotropic drugs are associated with suicide ideation in adults, evidence of this association in adolescents remains limited.<BR><B>OBJECTIVE: </B>To investigate the relationship between suicide ideation and psychotropic recreational drug use among adolescents.<BR><B>METHODS: </B>Systematic review with meta-analysis developed at Universidade Federal de Uberlândia (UFU) and Universidade Estadual de Campinas (UNICAMP), Brazil.<BR><B>METHODS: </B>A search across eight electronic databases for observational studies, without language or publication year restrictions, was conducted. The Joanna Briggs Institute tool was used to assess the risk of bias. Random-effects meta-analyses and odds ratios were used to measure the effects.<BR><B>RESULTS: </B>The search yielded 19,732 studies, of which 78 were included in the qualitative synthesis and 32 in the meta-analysis. The findings indicated that suicidal ideation was 1.96 times more likely (95% confidence interval, CI = 1.47; 2.61) for adolescents who used some drug recurrently and 3.32 times more likely (95%CI = 1.86; 5.93) among those who abused drugs. Additionally, adolescents who used cannabis were 1.57 times more likely (95%CI = 1.34; 1.84) to experience suicide ideation compared with non-users, while cocaine users had 2.57 times higher odds (95%CI = 1.47; 4.50).<BR><B>CONCLUSIONS: </B>Psychotropic recreational drug use is associated with suicidal ideation among adolescents regardless of current or previous use, abuse, or type of substance used.<BR><B>BACKGROUND: </B>Registered in the PROSPERO database under the identification number CRD42021232360. https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021232360.