PDF(Pubmed)
Abstract：
OBJECTIVE: Severe maxillofacial space infection (MSI) as an end stage of dentoalveolar diseases or complication of sialadenitis is a potentially life-threatening disease accompanied by complications including airway obstruction, jugular vein thrombosis, descending mediastinitis, sepsis and acute respiratory distress syndrome. The aim of this study was to analyze the incidence and time trends of severe MSI and potentially influencing factors in the German healthcare system over time.
METHODS: Nationwide data regarding the national diagnosis-related-group (DRG) inpatient billing system was received from the German Federal Statistical Office. A retrospective analysis of incidence and time trends of MSI-associated procedures classified with the Operation and Procedure Classification System (OPS), were statistically evaluated using Poisson regression analysis between 2005 and 2022 and were associated with different epidemiological factors.
RESULTS: The total standardized incidence rate of MSI-associated procedures in the observational period 2005-2022 was 9.8 (♀8.2; ♂11.4) per 100,000 person years. For all age groups a significant increase of 46.1% in severe MSI - related surgical interventions was registered within the observational period. The largest increase (120.5%) was found in elderly patients over 80 years. There were significant differences of the incidences of MSI-associated surgeries between the different federal states in Germany.
CONCLUSIONS: Severe MSI are a growing challenge in German health care especially among elderly patients over 80 years.
CONCLUSIONS: Severe MSI is a promising target for prevention. There should be more focus in primary dental and medical care especially in groups depending on social support.
METHODS: Nationwide data regarding the national diagnosis-related-group (DRG) inpatient billing system was received from the German Federal Statistical Office. A retrospective analysis of incidence and time trends of MSI-associated procedures classified with the Operation and Procedure Classification System (OPS), were statistically evaluated using Poisson regression analysis between 2005 and 2022 and were associated with different epidemiological factors.
RESULTS: The total standardized incidence rate of MSI-associated procedures in the observational period 2005-2022 was 9.8 (♀8.2; ♂11.4) per 100,000 person years. For all age groups a significant increase of 46.1% in severe MSI - related surgical interventions was registered within the observational period. The largest increase (120.5%) was found in elderly patients over 80 years. There were significant differences of the incidences of MSI-associated surgeries between the different federal states in Germany.
CONCLUSIONS: Severe MSI are a growing challenge in German health care especially among elderly patients over 80 years.
CONCLUSIONS: Severe MSI is a promising target for prevention. There should be more focus in primary dental and medical care especially in groups depending on social support.
摘要：
目的：严重颌面部间隙感染（MSI）作为牙槽病的终末期或唾液腺炎的并发症是一种潜在的危及生命的疾病，并伴有包括气道阻塞在内的并发症，颈静脉血栓形成,下行纵隔炎,脓毒症和急性呼吸窘迫综合征。这项研究的目的是分析德国医疗系统中严重MSI的发生率和时间趋势以及潜在的影响因素。
方法：关于国家诊断相关组（DRG）住院系统的全国数据来自德国联邦统计局。对操作和程序分类系统（OPS）分类的MSI相关程序的发生率和时间趋势进行回顾性分析，在2005年至2022年之间使用泊松回归分析进行统计评估，并与不同的流行病学因素相关。
结果：在2005-2022年的观察期内，与MSI相关的程序的总标准化发生率为每100,000人年9.8（8.2‰;and11.4）。在观察期内，所有年龄组的严重MSI相关手术干预措施显着增加了46.1％。在80岁以上的老年患者中发现了最大的增长（120.5％）。德国不同联邦州之间MSI相关手术的发生率存在显着差异。
结论：严重的MSI在德国的医疗保健中是一个日益严重的挑战，尤其是在80岁以上的老年患者中。
结论：严重MSI是一个有希望的预防目标。应该更加关注初级牙科和医疗护理，特别是在依赖于社会支持的群体中。
方法：关于国家诊断相关组（DRG）住院系统的全国数据来自德国联邦统计局。对操作和程序分类系统（OPS）分类的MSI相关程序的发生率和时间趋势进行回顾性分析，在2005年至2022年之间使用泊松回归分析进行统计评估，并与不同的流行病学因素相关。
结果：在2005-2022年的观察期内，与MSI相关的程序的总标准化发生率为每100,000人年9.8（8.2‰;and11.4）。在观察期内，所有年龄组的严重MSI相关手术干预措施显着增加了46.1％。在80岁以上的老年患者中发现了最大的增长（120.5％）。德国不同联邦州之间MSI相关手术的发生率存在显着差异。
结论：严重的MSI在德国的医疗保健中是一个日益严重的挑战，尤其是在80岁以上的老年患者中。
结论：严重MSI是一个有希望的预防目标。应该更加关注初级牙科和医疗护理，特别是在依赖于社会支持的群体中。
