Abstract：
HCA resection is crucial to prevent bleeding and malignant transformation. The aim of this study was to enhance the precision of tumor resection in hepatocellular adenoma (HCA) through the combination of intraoperative ultrasound (IOUS) and indocyanine green (ICG) fluorescence imaging. ICG was intravenously injected 24 h before surgery, enabling positive staining of HCA nodules. IOUS guided the parenchymal transection performed using the RoboLap approach. IOUS combined with ICG effectively demarcated lesions, allowing precision surgery while sparing healthy liver tissue. Intraoperative frozen examination further validated the potential of ICG to identify previously undetected lesions. The study showed promising advantages of ICG in HCA resections, potentially reducing the risk of recurrence and malignant transformation. The combined robotic and laparoscopic approach improved the feasibility of parenchymal-sparing surgery, offering a cautious assessment of HCA lesions.
摘要：
HCA切除术对于防止出血和恶性转化至关重要。本研究的目的是通过结合术中超声（IOUS）和吲哚菁绿（ICG）荧光成像来提高肝细胞腺瘤（HCA）肿瘤切除的精度。手术前24小时静脉注射ICG，使HCA结节呈阳性染色。IOUS指导使用RoboLap方法进行的实质横切。IOUS联合ICG有效标定病变，允许精确手术，同时保留健康的肝脏组织。术中冷冻检查进一步验证了ICG识别先前未检测到的病变的潜力。该研究显示ICG在HCA切除中具有良好的优势，可能降低复发和恶性转化的风险。机器人和腹腔镜相结合的方法提高了保留实质手术的可行性，提供对HCA病变的谨慎评估。
