Abstract：
Leptospirosis is a (re) emerging zoonosis that occurs worldwide. This study aimed to assess seroprevalence of leptospirosis and to identify the most common reactive serovars and risk factors for seropositivity in apparently healthy stray dogs of unknown vaccination status in the Sarajevo region of Bosnia and Herzegovina. Positive microscopic agglutination test titres (≥ 1:25) were detected in 3.87% (156/4028) of samples and most of the sera reacted against one serovar (85.9%). Dogs were most commonly reactive to Canicola (40.4%) and Hardjo (33.3%), followed by Pomona (15.4%) Tarassovi (14.7%), Icterohaemorrhagiae (8.3%), Grippotyphosa (5.8%), Bratislava (1.3%) and Saxkoebing (0.6%). Dogs older than one year had higher odds of seropositivity compared to younger dogs. The seropositivity was higher in spring and autumn than in summer. These results advocate for the need of a control strategy for this zoonosis in the country, which should include sero-surveillance, monitoring, and the inclusion of additional serovars in the testing.
摘要：
钩端螺旋体病是全球范围内发生的一种（重新）新兴的人畜共患病。这项研究旨在评估钩端螺旋体病的血清阳性率，并确定波斯尼亚和黑塞哥维那萨拉热窝地区疫苗接种状态未知的明显健康的流浪狗中最常见的反应性血清和血清阳性的危险因素。在3.87％（156/4028）的样品中检测到阳性的显微镜凝集试验滴度（≥1：25），并且大多数血清对一种血清变体（85.9％）反应。狗对Canicola（40.4％）和Hardjo（33.3％）最常见，其次是波莫纳(15.4%)塔拉索维(14.7%)，肺出血(8.3%),Gripotyphosa(5.8%),布拉迪斯拉发（1.3%）和萨克斯克宾（0.6%）。与年轻的狗相比，一岁以上的狗的血清阳性几率更高。春季和秋季的血清阳性率高于夏季。这些结果主张在该国需要针对这种人畜共患病的控制策略，其中应该包括血清监测，监测,并在测试中加入额外的血清型。
