PDF(Pubmed)
Abstract：
BACKGROUND: There is only limited information about the health effects of regular vaping. Research on the health status of people who used to smoke faces the challenge that previous smoking may have caused unknown health effects. Only studies of people who vape but have never smoked combustible cigarettes can enable the detection of harms attributable to vaping. Large prospective studies of well-characterized electronic cigarette users with and without a history of combustible cigarette smoking are warranted to establish the long-term effects of regular vaping on respiratory health.
OBJECTIVE: We will conduct a global cross-sectional survey of individuals from 6 world regions. Respiratory symptoms will be assessed using a validated questionnaire-the Respiratory Symptom Experience Scale (RSES). Current vapers who are nonusers of other tobacco or nicotine products will be compared with matched controls who are nonusers of vapes and other tobacco or nicotine products.
METHODS: This will be a multicountry, cross-sectional internet-based survey of 750 adults aged ≥18 years who satisfy the criteria for inclusion in either a cohort of people who exclusively vape and who are nonusers of other tobacco or nicotine products (\"vapers cohort\"; target N=500) or a cohort of nonvapers who are also nonusers of other tobacco or nicotine products (\"controls cohort\"; target N=250). The primary end point of the study is the RSES score. RSES scores of people in the \"vapers cohort\" will be compared with those of people in the \"controls cohort.\" Additionally, the study will collect data to characterize patterns of vaping product use among the vapers cohort. Data collection will include information about the age initiation of using vape products, reasons for starting and continuing the use of vape products, specific types of products used, flavors and nicotine strengths of recently used products, as well as the frequency and intensity of product use in the past 30 days.
RESULTS: Participant recruitment started in April 2023, and enrollment was completed by November 2023 with 748 participants. Results will be reported in 2024.
CONCLUSIONS: This will be the first study providing key insights into respiratory health effects associated with using electronic cigarettes in people who vape with no established use of combustible cigarettes or other tobacco or nicotine products.
UNASSIGNED: DERR1-10.2196/54236.
OBJECTIVE: We will conduct a global cross-sectional survey of individuals from 6 world regions. Respiratory symptoms will be assessed using a validated questionnaire-the Respiratory Symptom Experience Scale (RSES). Current vapers who are nonusers of other tobacco or nicotine products will be compared with matched controls who are nonusers of vapes and other tobacco or nicotine products.
METHODS: This will be a multicountry, cross-sectional internet-based survey of 750 adults aged ≥18 years who satisfy the criteria for inclusion in either a cohort of people who exclusively vape and who are nonusers of other tobacco or nicotine products (\"vapers cohort\"; target N=500) or a cohort of nonvapers who are also nonusers of other tobacco or nicotine products (\"controls cohort\"; target N=250). The primary end point of the study is the RSES score. RSES scores of people in the \"vapers cohort\" will be compared with those of people in the \"controls cohort.\" Additionally, the study will collect data to characterize patterns of vaping product use among the vapers cohort. Data collection will include information about the age initiation of using vape products, reasons for starting and continuing the use of vape products, specific types of products used, flavors and nicotine strengths of recently used products, as well as the frequency and intensity of product use in the past 30 days.
RESULTS: Participant recruitment started in April 2023, and enrollment was completed by November 2023 with 748 participants. Results will be reported in 2024.
CONCLUSIONS: This will be the first study providing key insights into respiratory health effects associated with using electronic cigarettes in people who vape with no established use of combustible cigarettes or other tobacco or nicotine products.
UNASSIGNED: DERR1-10.2196/54236.
摘要：
背景：关于常规电子烟对健康的影响的信息有限。对曾经吸烟的人的健康状况进行研究面临的挑战是，以前的吸烟可能会对健康造成未知的影响。只有对vape但从未吸过可燃香烟的人的研究才能检测到vaping造成的危害。有必要对有和没有可燃吸烟史的特征良好的电子烟使用者进行大规模的前瞻性研究，以确定定期雾化对呼吸道健康的长期影响。
目的：我们将对来自世界6个地区的个人进行全球横断面调查。将使用经过验证的问卷-呼吸症状体验量表（RSES）评估呼吸症状。当前非其他烟草或尼古丁产品使用者的vapers将与非vapes和其他烟草或尼古丁产品使用者的匹配对照进行比较。
方法：这将是一个多国家，对750名年龄≥18岁的成年人进行横断面调查,这些成年人符合纳入仅使用vape且非使用其他烟草或尼古丁产品的人群(“vapers队列”;目标N=500)或非使用其他烟草或尼古丁产品的非vapers人群(“对照队列”;目标N=250)的标准.研究的主要终点是RSES评分。将“vapers队列”中的人的RSES得分与“控制组”中的人的得分进行比较。\"此外，这项研究将收集数据，以表征vapers队列中vaping产品使用的模式。数据收集将包括有关使用vape产品的年龄开始的信息，开始和继续使用vape产品的原因，使用的特定类型的产品，最近使用的产品的风味和尼古丁强度，以及过去30天内产品使用的频率和强度。
结果：参与者招募于2023年4月开始，到2023年11月完成注册，有748名参与者。结果将在2024年报告。
结论：这将是第一项研究，为在没有确定使用可燃香烟或其他烟草或尼古丁产品的情况下使用电子烟的人的呼吸健康影响提供关键见解。
■DERR1-10.2196/54236。
目的：我们将对来自世界6个地区的个人进行全球横断面调查。将使用经过验证的问卷-呼吸症状体验量表（RSES）评估呼吸症状。当前非其他烟草或尼古丁产品使用者的vapers将与非vapes和其他烟草或尼古丁产品使用者的匹配对照进行比较。
方法：这将是一个多国家，对750名年龄≥18岁的成年人进行横断面调查,这些成年人符合纳入仅使用vape且非使用其他烟草或尼古丁产品的人群(“vapers队列”;目标N=500)或非使用其他烟草或尼古丁产品的非vapers人群(“对照队列”;目标N=250)的标准.研究的主要终点是RSES评分。将“vapers队列”中的人的RSES得分与“控制组”中的人的得分进行比较。\"此外，这项研究将收集数据，以表征vapers队列中vaping产品使用的模式。数据收集将包括有关使用vape产品的年龄开始的信息，开始和继续使用vape产品的原因，使用的特定类型的产品，最近使用的产品的风味和尼古丁强度，以及过去30天内产品使用的频率和强度。
结果：参与者招募于2023年4月开始，到2023年11月完成注册，有748名参与者。结果将在2024年报告。
结论：这将是第一项研究，为在没有确定使用可燃香烟或其他烟草或尼古丁产品的情况下使用电子烟的人的呼吸健康影响提供关键见解。
■DERR1-10.2196/54236。
