PDF(Pubmed)
Abstract：
BACKGROUND: Preeclampsia is a significant complication that occurs during the second half of pregnancy. Recent studies have indicated that dietary factors play a crucial role in the development of preeclampsia. The Diet Quality Index-International (DQI-I) and Dietary Diversity Score (DDS) are appropriate indices for assessing the quality of foods, meals, and diets. This study aimed to investigate the relationship between DQI-I, DDS, and preeclampsia.
METHODS: This study utilized a case-control design. A total of 90 newly diagnosed preeclampsia cases and 90 healthy controls were included from a referral hospital in Tabriz, Iran. DQI-I and DDS were calculated based on information obtained from a reliable Food Frequency Questionnaire consisting of 168 food items, which assessed participants\' usual diet. Logistic regression analysis adjusted for age, body mass index, education, family history of preeclampsia, and total energy intake was used to estimate odds ratios (ORs).
RESULTS: The mean age and pre-pregnancy body mass index of the participants were: 27.14 ± 4.40 years and 26.09 ± 3.33 kg/m2, respectively. After adjusting for various confounders, we found significant inverse association between the risk of developing preeclampsia and both DQI-I and DDS. The highest quartile of DQI-I had a significantly lower risk of developing preeclampsia compared to the first quartile (OR = 0.02, 95% CI [0.005, 0.08]) (P < 0.001). Similarly, the highest quartile of DDS had a significantly lower risk of developing preeclampsia compared to the first quartile (OR = 0.09, 95% CI [0.03, 0.31]) (P = 0.001).
CONCLUSIONS: Our findings suggest that maintaining a high-quality and diverse diet is associated with a lower risk of preeclampsia. Further studies are needed to confirm these associations and explore potential causal relationships.
METHODS: This study utilized a case-control design. A total of 90 newly diagnosed preeclampsia cases and 90 healthy controls were included from a referral hospital in Tabriz, Iran. DQI-I and DDS were calculated based on information obtained from a reliable Food Frequency Questionnaire consisting of 168 food items, which assessed participants\' usual diet. Logistic regression analysis adjusted for age, body mass index, education, family history of preeclampsia, and total energy intake was used to estimate odds ratios (ORs).
RESULTS: The mean age and pre-pregnancy body mass index of the participants were: 27.14 ± 4.40 years and 26.09 ± 3.33 kg/m2, respectively. After adjusting for various confounders, we found significant inverse association between the risk of developing preeclampsia and both DQI-I and DDS. The highest quartile of DQI-I had a significantly lower risk of developing preeclampsia compared to the first quartile (OR = 0.02, 95% CI [0.005, 0.08]) (P < 0.001). Similarly, the highest quartile of DDS had a significantly lower risk of developing preeclampsia compared to the first quartile (OR = 0.09, 95% CI [0.03, 0.31]) (P = 0.001).
CONCLUSIONS: Our findings suggest that maintaining a high-quality and diverse diet is associated with a lower risk of preeclampsia. Further studies are needed to confirm these associations and explore potential causal relationships.
摘要：
背景：先兆子痫是在妊娠后半期发生的重要并发症。最近的研究表明，饮食因素在先兆子痫的发生发展中起着至关重要的作用。国际饮食质量指数(DQI-I)和饮食多样性评分(DDS)是评估食物质量的适当指标,饭菜,和饮食。本研究旨在探讨DQI-I，DDS,和先兆子痫.
方法：本研究采用病例对照设计。共有90例新诊断的先兆子痫病例和90例健康对照来自大不里士的转诊医院，伊朗。DQI-I和DDS是根据从可靠的食物频率问卷中获得的信息计算的，该问卷由168种食物组成，评估参与者的日常饮食。Logistic回归分析调整年龄，身体质量指数,教育,先兆子痫家族史,总能量摄入用于估计比值比(ORs).
结果：参与者的平均年龄和孕前体重指数分别为：27.14±4.40岁和26.09±3.33kg/m2。在调整了各种混杂因素后，我们发现先兆子痫的发病风险与DQI-I和DDS呈显著负相关.与第一四分位数相比，DQI-I的最高四分位数发生先兆子痫的风险显着降低（OR=0.02，95％CI[0.005，0.08]）（P<0.001）。同样，与第一四分位数相比,DDS的最高四分位数发生先兆子痫的风险显著降低(OR=0.09,95%CI[0.03,0.31])(P=0.001).
结论：我们的研究结果表明，保持高质量和多样化的饮食与降低先兆子痫的风险有关。需要进一步的研究来确认这些关联并探索潜在的因果关系。
方法：本研究采用病例对照设计。共有90例新诊断的先兆子痫病例和90例健康对照来自大不里士的转诊医院，伊朗。DQI-I和DDS是根据从可靠的食物频率问卷中获得的信息计算的，该问卷由168种食物组成，评估参与者的日常饮食。Logistic回归分析调整年龄，身体质量指数,教育,先兆子痫家族史,总能量摄入用于估计比值比(ORs).
结果：参与者的平均年龄和孕前体重指数分别为：27.14±4.40岁和26.09±3.33kg/m2。在调整了各种混杂因素后，我们发现先兆子痫的发病风险与DQI-I和DDS呈显著负相关.与第一四分位数相比，DQI-I的最高四分位数发生先兆子痫的风险显着降低（OR=0.02，95％CI[0.005，0.08]）（P<0.001）。同样，与第一四分位数相比,DDS的最高四分位数发生先兆子痫的风险显著降低(OR=0.09,95%CI[0.03,0.31])(P=0.001).
结论：我们的研究结果表明，保持高质量和多样化的饮食与降低先兆子痫的风险有关。需要进一步的研究来确认这些关联并探索潜在的因果关系。
