Abstract:
Retinoblastoma is the most common eye malignancy in children that if left untreated can invade intraocular structures, metastasize, and rarely lead to death. Traditionally treated with systemic chemotherapy, Intra-arterial chemotherapy is gaining popularity as it allows for the direct administration of chemotherapy through the ophthalmic artery, thus reducing systemic side effects. Intra-arterial chemotherapy procedures have evolved, with refinements to reduce risks and radiation exposure. Intra-arterial chemotherapy boasts an impressive technical success rate and one year ocular survival even amongst advanced cases. This review offers a thorough examination of the technique, indications, contraindications, outcomes, and alternative options for Intra-arterial chemotherapy.
摘要:
视网膜母细胞瘤是儿童最常见的眼部恶性肿瘤,如果不及时治疗可侵入眼内结构,转移,很少导致死亡。传统上接受全身化疗,动脉内化疗越来越受欢迎,因为它允许通过眼动脉直接进行化疗,从而减少全身副作用。动脉内化疗程序已经发展,进行改进以减少风险和辐射暴露。即使在晚期病例中,动脉内化疗也具有令人印象深刻的技术成功率和一年的眼生存率。这篇综述提供了对该技术的彻底检查,适应症,禁忌症,结果,和动脉内化疗的替代选择。