%0 Journal Article
%T Advanced Interventional Treatments in Retinoblastoma Management: A Comprehensive Review.
%A Kolyvas P
%A Mir A
%A Stirrat T
%A Brookner B
%A Pilar N
%A Monroe E
%A Ahuja R
%J Cardiovasc Intervent Radiol
%V 47
%N 4
%D 2024 Apr 20
%M 38509339
%F 2.797
%R 10.1007/s00270-024-03692-2
%X Retinoblastoma is the most common eye malignancy in children that if left untreated can invade intraocular structures, metastasize, and rarely lead to death. Traditionally treated with systemic chemotherapy, Intra-arterial chemotherapy is gaining popularity as it allows for the direct administration of chemotherapy through the ophthalmic artery, thus reducing systemic side effects. Intra-arterial chemotherapy procedures have evolved, with refinements to reduce risks and radiation exposure. Intra-arterial chemotherapy boasts an impressive technical success rate and one year ocular survival even amongst advanced cases. This review offers a thorough examination of the technique, indications, contraindications, outcomes, and alternative options for Intra-arterial chemotherapy.