PDF(Pubmed)
Abstract：
Postexercise blood pressure (BP) may be a better predictor of cardiovascular risk than office BP, but there is a lack of data supporting this claim. We hypothesized that postexercise BP may be an important prognostic marker. Our aim was to evaluate the association of postexercise BP with major adverse cardiovascular events (MACE) and all-cause mortality. A total of 2581 participants (median age, 46 years; 55.9% women) from the Coronary Artery Risk Development in Young Adults study at year 20 (2005-2006) who underwent a graded exercise treadmill test using a modified Balke graded protocol were included. Postexercise BP was measured at baseline. Cox models were used to estimate the associations of postexercise BP with MACE and all-cause mortality. Participants were followed up until December 31, 2021. In the entire population, postexercise systolic BP showed no significant association with MACE or all-cause mortality, while postexercise diastolic BP was associated with MACE (hazard ratios [HR], 1.27 [95% CI, 1.06-1.52], per 10 mmHg increase) and all-cause mortality (HR, 1.26 [95% CI, 1.05-1.51], per 10 mmHg increase). In the normal BP group, postexercise systolic BP was not significantly associated with MACE or all-cause mortality, and postexercise diastolic BP was strongly associated with MACE (HR, 1.57 [95% CI, 1.18-2.09], per 10 mmHg increase). In this population-based cohort study, postexercise diastolic BP was significantly associated with the risk of MACE and all-cause mortality. Among individuals with normal BP, postexercise diastolic BP could identify those at a higher risk of cardiovascular events.
摘要：
运动后血压（BP）可能比办公室血压更好地预测心血管风险，但是缺乏支持这一说法的数据。我们假设运动后BP可能是一个重要的预后指标。我们的目的是评估运动后BP与主要不良心血管事件（MACE）和全因死亡率的关系。共有2581名参与者(平均年龄，46岁；55.9％的女性）来自20年（2005-2006年）的年轻人冠状动脉风险发展研究，他们使用改良的Balke分级方案进行了分级运动跑步机测试。在基线时测量运动后BP。Cox模型用于估计运动后BP与MACE和全因死亡率的关系。参与者被跟踪到2021年12月31日。在整个人口中，运动后收缩压与MACE或全因死亡率无显著关联,而运动后舒张压与MACE相关(风险比[HR]，1.27[95%CI，1.06-1.52]，每10mmHg增加)和全因死亡率(HR，1.26[95%CI，1.05-1.51]，每增加10mmHg)。在正常血压组,运动后收缩压与MACE或全因死亡率无显著相关,运动后舒张压与MACE密切相关(HR，1.57[95%CI，1.18-2.09]，每增加10mmHg)。在这项基于人群的队列研究中，运动后舒张压与MACE风险和全因死亡率显著相关.在血压正常的个体中，运动后舒张压可以确定心血管事件风险较高的人群.
