PDF(Pubmed)
Abstract：
The genetic diversity analysis of six dog breeds, including Ca de Bestiar (CB), Ca de Bou (CBOU), Podenco Ibicenco (PI), Ca Rater (CR), Ca Mè (CM), and Ca de Conills (CC), reveals insightful findings. CB showcases the highest mean number of alleles (6.17) and heterozygosity values, with significant deviations from Hardy-Weinberg equilibrium (HWE) observed in five markers, indicating high intra-racial genetic diversity (average observed heterozygosity (Ho) = 0.754, expected heterozygosity (He) = 0.761). In contrast, CBOU presents the lowest mean number of alleles (5.05) and heterozygosity values, coupled with moderate polymorphic information content (PIC) values and a moderate level of intra-racial genetic diversity (average Ho = 0.313, He = 0.394). PI demonstrates moderate genetic diversity with an average of 5.75 alleles and highly informative PIC values, while CR displays robust genetic diversity with an average of 6.61 alleles and deviations from equilibrium, indicating potential risks of inbreeding (average Ho = 0.563, He = 0.658). CM exhibits moderate genetic diversity and deviations from equilibrium, similar to CBOU, with an average of 6.5 alleles and moderate PIC values (average Ho = 0.598, He = 0.676). Conversely, CC shows a wider range of allelic diversity and deviations from equilibrium (average Ho = 0.611, He = 0.706), suggesting a more diverse genetic background. Inter-racial analysis underscores distinct genetic differentiation between breeds, emphasizing the importance of informed breeding decisions and proactive genetic management strategies to preserve diversity, promote breed health, and ensure long-term sustainability across all breeds studied.
摘要：
6个犬种的遗传多样性分析,包括CadeBetiar(CB)，CadeBou(CBOU)，PodencoIbicenco(PI),Ca评分器(CR)，CaMè(CM),和CadeConills(CC)，揭示了深刻的发现。CB表现出最高的等位基因平均数(6.17)和杂合性值，在五个标记中观察到与Hardy-Weinberg平衡(HWE)的显著偏差，表明种族内遗传多样性高（平均观察杂合性（Ho）=0.754，预期杂合性（He）=0.761）。相比之下,CBOU呈现最低的平均等位基因数（5.05）和杂合性值，加上中等的多态信息含量（PIC）值和中等水平的种族内遗传多样性（平均Ho=0.313，He=0.394）。PI表现出中等的遗传多样性，平均有5.75个等位基因和高度信息的PIC值，而CR表现出稳健的遗传多样性，平均为6.61个等位基因，偏离平衡，表明近亲繁殖的潜在风险(平均Ho=0.563，He=0.658)。CM表现出适度的遗传多样性和对平衡的偏离，类似于CBOU，平均6.5个等位基因和中等PIC值（平均Ho=0.598，He=0.676）。相反，CC显示出更广泛的等位基因多样性和与平衡的偏差（平均Ho=0.611，He=0.706），表明了更多样化的遗传背景。种族间分析强调了品种之间不同的遗传差异，强调明智的育种决策和积极的遗传管理策略以保护多样性的重要性，促进品种健康，并确保所有研究品种的长期可持续性。
