PDF(Pubmed)
Abstract：
BACKGROUND: Telocytes are modified interstitial cells that communicate with other types of cells, including stem cells. Stemness properties render them more susceptible to environmental conditions. The current morphological investigation examined the reactions of telocytes to salt stress in relation to stem cells and myoblasts. The common carp are subjected to salinity levels of 0.2, 6, and 10 ppt. The gill samples were preserved and prepared for TEM.
RESULTS: The present study observed that telocytes undergo morphological change and exhibit enhanced secretory activities in response to changes in salinity. TEM can identify typical telocytes. This research gives evidence for the communication of telocytes with stem cells, myoblasts, and skeletal muscles. Telocytes surround stem cells. Telopodes made planar contact with the cell membrane of the stem cell. Telocytes and their telopodes surrounded the skeletal myoblast. These findings show that telocytes may act as nurse cells for skeletal stem cells and myoblasts, which undergo fibrillogenesis. Not only telocytes undergo morphological alternations, but also skeletal muscles become hypertrophied, which receive telocyte secretory vesicles in intercellular compartments.
CONCLUSIONS: In conclusion, the activation of telocytes is what causes stress adaptation. They might act as important players in intercellular communication between cells. It is also possible that reciprocal interaction occurs between telocytes and other cells to adapt to changing environmental conditions.
RESULTS: The present study observed that telocytes undergo morphological change and exhibit enhanced secretory activities in response to changes in salinity. TEM can identify typical telocytes. This research gives evidence for the communication of telocytes with stem cells, myoblasts, and skeletal muscles. Telocytes surround stem cells. Telopodes made planar contact with the cell membrane of the stem cell. Telocytes and their telopodes surrounded the skeletal myoblast. These findings show that telocytes may act as nurse cells for skeletal stem cells and myoblasts, which undergo fibrillogenesis. Not only telocytes undergo morphological alternations, but also skeletal muscles become hypertrophied, which receive telocyte secretory vesicles in intercellular compartments.
CONCLUSIONS: In conclusion, the activation of telocytes is what causes stress adaptation. They might act as important players in intercellular communication between cells. It is also possible that reciprocal interaction occurs between telocytes and other cells to adapt to changing environmental conditions.
摘要：
背景：末端细胞是修饰的间质细胞，与其他类型的细胞进行交流，包括干细胞.树干特性使它们更容易受到环境条件的影响。当前的形态学研究检查了端粒细胞对与干细胞和成肌细胞相关的盐应激的反应。鲤鱼的盐度水平为0.2、6和10ppt。保存并准备g样品用于TEM。
结果：本研究观察到端粒细胞发生形态变化，并表现出响应盐度变化的分泌活性增强。TEM可以识别典型的端粒细胞。这项研究提供了端粒细胞与干细胞通讯的证据，成肌细胞,和骨骼肌。末端细胞围绕干细胞。Telopodes与干细胞的细胞膜平面接触。子端细胞及其端足细胞包围着骨骼肌成肌细胞。这些发现表明，端粒细胞可能充当骨骼干细胞和成肌细胞的护士细胞，经历原纤维形成。不仅末端细胞经历形态变化，而且骨骼肌也变得肥大，在细胞间隔室中接受端粒细胞分泌囊泡。
结论：结论：末端细胞的激活是导致压力适应的原因。它们可能在细胞间的细胞间通讯中起重要作用。也可能在末端细胞和其他细胞之间发生相互作用以适应变化的环境条件。
结果：本研究观察到端粒细胞发生形态变化，并表现出响应盐度变化的分泌活性增强。TEM可以识别典型的端粒细胞。这项研究提供了端粒细胞与干细胞通讯的证据，成肌细胞,和骨骼肌。末端细胞围绕干细胞。Telopodes与干细胞的细胞膜平面接触。子端细胞及其端足细胞包围着骨骼肌成肌细胞。这些发现表明，端粒细胞可能充当骨骼干细胞和成肌细胞的护士细胞，经历原纤维形成。不仅末端细胞经历形态变化，而且骨骼肌也变得肥大，在细胞间隔室中接受端粒细胞分泌囊泡。
结论：结论：末端细胞的激活是导致压力适应的原因。它们可能在细胞间的细胞间通讯中起重要作用。也可能在末端细胞和其他细胞之间发生相互作用以适应变化的环境条件。
