PDF(Pubmed)
Abstract：
OBJECTIVE: To analyze torpedo maculopathy (TM) and to report the characteristics of the disease.
METHODS: Retrospective study. The review of a database for clinical diagnosis identified eight patients with TM lesions in the retina between 2016 and 2022. Multimodal imaging was used to analyze the cases.
RESULTS: All cases were unilateral, asymptomatic, and hypopigmented. They were associated by surrounding hyperpigmented retinal pigment epithelium changes to varying degrees. All lesions were located in the temporal retina on the horizontal axis, pointing towards the fovea, except for one patient with a lesion inferior to the fovea. Optical coherence tomography imaging revealed a normal inner retina in all eyes. In the area of the TM lesion, attenuation of the interdigitation zone was seen in mild cases (three cases). All other five patients had thinning of the outer nuclear layer and loss of ellipsoid zone and interdigitation zone of the TM lesion. Four of these cases had a subretinal cavitation/cleft, and two of them additionally an inner choroidal excavation. No patient had any sign of choroidal neovascularization. The average age for patients with type 1 TM was 18 years and for type 2 TM 16.5 years.
CONCLUSIONS: In this large case series, we could not detect an age difference between the different types of the TM. Contrary to previous discussions, type 2 TM can also occur in young patients.
METHODS: Retrospective study. The review of a database for clinical diagnosis identified eight patients with TM lesions in the retina between 2016 and 2022. Multimodal imaging was used to analyze the cases.
RESULTS: All cases were unilateral, asymptomatic, and hypopigmented. They were associated by surrounding hyperpigmented retinal pigment epithelium changes to varying degrees. All lesions were located in the temporal retina on the horizontal axis, pointing towards the fovea, except for one patient with a lesion inferior to the fovea. Optical coherence tomography imaging revealed a normal inner retina in all eyes. In the area of the TM lesion, attenuation of the interdigitation zone was seen in mild cases (three cases). All other five patients had thinning of the outer nuclear layer and loss of ellipsoid zone and interdigitation zone of the TM lesion. Four of these cases had a subretinal cavitation/cleft, and two of them additionally an inner choroidal excavation. No patient had any sign of choroidal neovascularization. The average age for patients with type 1 TM was 18 years and for type 2 TM 16.5 years.
CONCLUSIONS: In this large case series, we could not detect an age difference between the different types of the TM. Contrary to previous discussions, type 2 TM can also occur in young patients.
摘要：
目的：分析鱼雷黄斑病（TM）并报告该病的特征。
方法：回顾性研究。对临床诊断数据库的审查确定了2016年至2022年之间8例视网膜中TM病变的患者。采用多模态成像对病例进行分析。
结果：所有病例均为单侧，无症状，色素减退.它们与周围色素沉着的视网膜色素上皮不同程度的变化有关。所有病变均位于颞叶视网膜的水平轴上，指向中央凹，除了一个患者的病灶位于中央凹下方。光学相干断层扫描成像显示所有眼睛的内部视网膜正常。在TM病变区域,在轻度病例（3例）中发现了交叉带的衰减。所有其他五名患者的外核层变薄，TM病变的椭圆体区和交叉区丢失。其中四例有视网膜下空洞/裂隙，其中两个还包括内部脉络膜开挖。没有患者有任何脉络膜新生血管的迹象。1型TM患者的平均年龄为18岁，2型TM患者的平均年龄为16.5岁。
结论：在这个大型案例系列中，我们无法检测到不同类型TM之间的年龄差异。与以前的讨论相反，2型TM也可发生在年轻患者中。
方法：回顾性研究。对临床诊断数据库的审查确定了2016年至2022年之间8例视网膜中TM病变的患者。采用多模态成像对病例进行分析。
结果：所有病例均为单侧，无症状，色素减退.它们与周围色素沉着的视网膜色素上皮不同程度的变化有关。所有病变均位于颞叶视网膜的水平轴上，指向中央凹，除了一个患者的病灶位于中央凹下方。光学相干断层扫描成像显示所有眼睛的内部视网膜正常。在TM病变区域,在轻度病例（3例）中发现了交叉带的衰减。所有其他五名患者的外核层变薄，TM病变的椭圆体区和交叉区丢失。其中四例有视网膜下空洞/裂隙，其中两个还包括内部脉络膜开挖。没有患者有任何脉络膜新生血管的迹象。1型TM患者的平均年龄为18岁，2型TM患者的平均年龄为16.5岁。
结论：在这个大型案例系列中，我们无法检测到不同类型TM之间的年龄差异。与以前的讨论相反，2型TM也可发生在年轻患者中。
