Abstract：
Extracorporeal photopheresis (ECP) has proven effective in the treatment of several diseases, including acute and chronic graft-versus-host disease (GVHD) after allogeneic hematopoietic stem cell transplantation. In its standard version, ECP requires leukapheresis to obtain a fraction of mononuclear cells. The possibility of using leukapheresis is limited by the requirements for vascular access and the somatic status of the patient. We have developed a new ECP method that does not require leukapheresis. This paper presents a description of two clinical cases of severe refractory GVHD treated by micro-ECP.
摘要：
体外光分离术（ECP）已被证明可有效治疗多种疾病，包括异基因造血干细胞移植后的急性和慢性移植物抗宿主病（GVHD）。在其标准版本中，ECP需要白细胞去除术以获得一部分单核细胞。使用白细胞去除术的可能性受到血管通路和患者身体状态的要求的限制。我们开发了一种新的ECP方法，不需要白细胞去除术。本文介绍了微ECP治疗严重难治性GVHD的2例临床病例。
