%0 Case Reports
%T Extracorporeal photopheresis: Is one ounce of blood enough? Case reports.
%A Kumukova I
%A Kurnikova E
%A Trakhtman P
%J Pediatr Blood Cancer
%V 71
%N 3
%D 2024 Mar 17
%M 38105463
%F 3.838
%R 10.1002/pbc.30800
%X Extracorporeal photopheresis (ECP) has proven effective in the treatment of several diseases, including acute and chronic graft-versus-host disease (GVHD) after allogeneic hematopoietic stem cell transplantation. In its standard version, ECP requires leukapheresis to obtain a fraction of mononuclear cells. The possibility of using leukapheresis is limited by the requirements for vascular access and the somatic status of the patient. We have developed a new ECP method that does not require leukapheresis. This paper presents a description of two clinical cases of severe refractory GVHD treated by micro-ECP.