PDF(Pubmed)
Abstract：
The temporal pole (TP) is considered one of the major paralimbic cortical regions, and is involved in a variety of functions such as sensory perception, emotion, semantic processing, and social cognition. Based on differences in cytoarchitecture, the TP can be further subdivided into smaller regions (dorsal, ventrolateral and ventromedial), each forming key nodes of distinct functional networks. However, the brain structural connectivity profile of TP subregions is not fully clarified. Using diffusion MRI data in a set of 31 healthy subjects, we aimed to elucidate the comprehensive structural connectivity of three cytoarchitectonically distinct TP subregions. Diffusion tensor imaging (DTI) analysis suggested that major association fiber pathways such as the inferior longitudinal, middle longitudinal, arcuate, and uncinate fasciculi provide structural connectivity to the TP. Further analysis suggested partially overlapping yet still distinct structural connectivity patterns across the TP subregions. Specifically, the dorsal subregion is strongly connected with wide areas in the parietal lobe, the ventrolateral subregion with areas including constituents of the default-semantic network, and the ventromedial subregion with limbic and paralimbic areas. Our results suggest the involvement of the TP in a set of extensive but distinct networks of cortical regions, consistent with its functional roles.
摘要：
颞极（TP）被认为是主要的旁皮层区域之一，并参与各种功能，如感官知觉，情感，语义处理，和社会认知。基于细胞结构的差异，TP可以进一步细分为更小的区域(背侧，腹外侧和腹内侧)，每个构成不同功能网络的关键节点。然而,TP亚区域的脑结构连接谱尚未完全阐明.使用一组31名健康受试者的扩散MRI数据，我们旨在阐明三个细胞结构上不同的TP亚区的综合结构连接.扩散张量成像（DTI）分析表明，主要的缔合纤维通路，如下纵线，中间纵向,弓形,和钩束为TP提供结构连接。进一步的分析表明，整个TP子区域的结构连接模式部分重叠，但仍然不同。具体来说,背侧分区与顶叶的广阔区域紧密相连，具有包括默认语义网络组成部分的区域的ventrolateral次区域，以及具有边缘和旁侧区域的腹内侧区域。我们的结果表明，TP参与了一组广泛但不同的皮质区域网络，与其功能角色一致。
