PDF(Pubmed)
Abstract：
The raccoon roundworm (Baylisascaris procyonis), a gastrointestinal nematode of the raccoon (Procyon lotor), may cause a severe form of larva migrans in humans, which can lead to death or permanent neurological damage. Although roundworms were inadvertently introduced to Europe alongside their raccoon hosts, the parasite is not present in every raccoon population. It is important to understand the geographic distribution of B. procyonis, as early and rapid treatment can prevent severe pathologies in humans. We present evidence for the roundworm spreading into a naive raccoon population through natural dispersal of infected raccoons. We sampled 181 raccoons from Saxony-Anhalt, a German federal state containing contact zones of different raccoon populations, two of which were previously free of the parasite. We screened the raccoons for roundworms and used microsatellite-based assignment tests to determine the genetic origin of the raccoons and their parasites. We detected roundworms in 16 of 45 raccoons sampled in a previously roundworm-free area in the northern part of the state. The largest proportion of the genetic ancestry (≥ 0.5) of the 16 raccoon hosts was assigned to the previously naive raccoon population. Conversely, the genetic ancestry of almost all the roundworms was assigned to the nearest roundworm population in the southern part of the state. Infected raccoons have, therefore, spread to the north of the state, where they interbred with and infected local raccoons. It seems likely that the roundworms will continue to spread. Health authorities should consider continuous surveillance programmes of naive populations and raise public awareness.
摘要：
浣熊蛔虫(Baylisascarisprocyonis)，浣熊的胃肠线虫（Procyonlotor），可能会导致人类严重的幼虫迁徙，会导致死亡或永久性神经损伤.尽管蛔虫与它们的浣熊宿主一起无意中被引入欧洲，这种寄生虫并不存在于每个浣熊种群中。重要的是要了解B.procyonis的地理分布，早期和快速治疗可以预防人类的严重病变。我们提供了证据，证明the虫通过自然传播被感染的浣熊而传播到幼稚的浣熊种群中。我们从萨克森-安哈尔特州采样了181只浣熊,德国联邦州包含不同浣熊种群的接触区，其中两个以前没有寄生虫。我们筛选了浣熊的蛔虫，并使用基于微卫星的分配测试来确定浣熊及其寄生虫的遗传起源。我们在该州北部以前没有round虫的地区采样的45只浣熊中的16只中检测到round虫。16个浣熊宿主中遗传祖先的最大比例（≥0.5）被分配给以前幼稚的浣熊种群。相反，几乎所有蛔虫的遗传祖先都被分配给该州南部最近的蛔虫种群。受感染的浣熊有，因此,蔓延到该州的北部，他们在那里与当地浣熊杂交并感染了浣熊。看起来蛔虫可能会继续传播。卫生当局应考虑对幼稚人群的持续监测计划，并提高公众意识。
