设计,合成 ,和选择性人类碳酸酐酶 II 的生物学研究 ,IX,和使用带有磺胺支架的 7 - 芳基 / 杂芳基三唑并嘧啶的 XII 抑制剂。
关键词: Carbonic anhydrase inhibitors [1,2,4]triazolo[15-a]pyrimidine antiproliferative activity structure–activity relationship sulphanilamide
Mesh : Humans Carbonic Anhydrase II / metabolism Structure-Activity Relationship Carbonic Anhydrase IX / metabolism Antigens, Neoplasm Carbonic Anhydrase I / metabolism Protein Isoforms Sulfanilamides Carbonic Anhydrase Inhibitors / pharmacology Molecular Structure
来 源:
DOI:10.1080/14756366.2023.2270180
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