PDF(Pubmed)
Abstract：
Graphene, fullerenes, diamond, carbon nanotubes, and carbon dots are just a few of the carbon-based nanomaterials that have gained enormous popularity in a variety of scientific disciplines and industrial uses. As a two-dimensional material in the creation of therapeutic delivery systems for many illnesses, nanosized graphene oxide (NGO) is now garnering a large amount of attention among these materials. In addition to other benefits, NGO functions as a drug nanocarrier with remarkable biocompatibility, high pharmaceutical loading capacity, controlled drug release capability, biological imaging efficiency, multifunctional nanoplatform properties, and the power to increase the therapeutic efficacy of loaded agents. Thus, NGO is a perfect nanoplatform for the development of drug delivery systems (DDSs) to both detect and treat a variety of ailments. This review article\'s main focus is on investigating surface functionality, drug-loading methods, and drug release patterns designed particularly for smart delivery systems. The paper also examines the relevance of using NGOs to build DDSs and considers prospective uses in the treatment of diseases including cancer, infection by bacteria, and bone regeneration medicine. These factors cover the use of naturally occurring medicinal substances produced from plant-based sources.
摘要：
石墨烯,富勒烯,钻石,碳纳米管,碳量子点只是碳基纳米材料中的一小部分，在各种科学学科和工业用途中获得了极大的普及。作为创建用于许多疾病的治疗递送系统的二维材料，纳米氧化石墨烯（NGO）现在在这些材料中引起了大量的关注。除了其他好处,非政府组织作为药物纳米载体具有显著的生物相容性，药物装载能力高，控制药物释放能力，生物成像效率，多功能纳米平台性能，以及增加负载剂的治疗功效的能力。因此，NGO是开发药物递送系统（DDS）以检测和治疗各种疾病的完美纳米平台。这篇评论文章的主要重点是研究表面功能，药物装载方法，以及专门为智能输送系统设计的药物释放模式。本文还研究了使用非政府组织建立DDS的相关性，并考虑了在治疗包括癌症在内的疾病中的预期用途。细菌感染，和骨再生医学。这些因素包括使用由植物来源产生的天然存在的药用物质。
