PDF(Pubmed)
Abstract：
By releasing an adequate amount of active ingredients when triggered by environmental and biological factors, the nanopesticides that respond to stimuli can enhance the efficacy of pesticides and contribute to the betterment of both the environment and food safety. The versatile nature and highly porous structure of metal-organic frameworks (MOFs) have recently garnered significant interest as drug carriers for various applications. In recent years, there has been significant progress in the development of metal-organic frameworks as nanocarriers for pesticide applications. This review focuses on the advancements, challenges, and potential future enhancements in the design of metal-organic frameworks as nanocarriers in the field of pesticides. We explore the various stimuli-responsive metal-organic frameworks carriers, particularly focusing on zeolitic imidazolate framework-8 (ZIF-8), which have been successfully activated by external stimuli such as pH-responsive or multiple stimuli-responsive mechanisms. In conclusion, this paper presents the existing issues and future prospects of metal-organic frameworks-based nanopesticides with stimuli-responsive controlled release.
摘要：
通过在环境和生物因素的触发下释放足够量的活性成分，响应刺激的纳米农药可以增强农药的功效，并有助于改善环境和食品安全。金属-有机骨架(MOF)的多功能性质和高度多孔结构最近作为用于各种应用的药物载体引起了极大的兴趣。近年来,在开发金属有机框架作为农药应用的纳米载体方面取得了重大进展。这次审查的重点是进步，挑战,以及未来在农药领域作为纳米载体的金属有机框架设计方面的潜在改进。我们探索了各种刺激响应金属有机框架载体，特别关注沸石咪唑酯骨架-8(ZIF-8)，已被外部刺激（如pH响应或多种刺激响应机制）成功激活。总之,本文介绍了基于金属有机骨架的刺激响应性控释纳米农药存在的问题和未来的前景。
