Abstract:
Oxalosis refers to the accumulation of calcium oxalate crystals in various organs and tissues, most commonly due to Aspergillus infection involving the lung or sinonasal tract. Both invasive and noninvasive forms of fungal rhinosinusitis can be associated with calcium oxalate crystal deposition. Here, we report a unique case of sinonasal oxalosis presenting as a destructive lesion in the absence of invasive fungal disease. Due to the clinical and pathologic significance of calcium oxalate crystals as seen in this patient, specimens from the sinonasal tract should be evaluated for the presence of these crystals, which may be a surrogate marker for fungal infection and may also independently cause tissue destruction.
摘要:
氧化是指草酸钙晶体在各种器官和组织中的积累,最常见于肺或鼻窦的曲霉菌感染。侵袭性和非侵袭性真菌性鼻窦炎都可能与草酸钙晶体沉积有关。这里,我们报告了一个独特的病例,在没有侵袭性真菌病的情况下表现为破坏性病变。由于该患者中草酸钙晶体的临床和病理意义,来自鼻窦的标本应评估这些晶体的存在,这可能是真菌感染的替代标记,也可能独立地导致组织破坏。