PDF(Pubmed)
Abstract：
Primary pulmonary salivary gland-type tumors are rare and characterized by a specific clinico-pathological manifestation. They are proximal tumors affecting young subjects and not associated with smoking. For optimal management, it is important to distinguish them from other bronchopulmonary tumors, with which they don´t share either biology or treatment and outcome. We conducted a retrospective study, including all primary malignant salivary gland-type tumors of the lung, over a period of 32 years, from January 1987 to December 2019. We collected data from the medical records of 10 patients: 5 men and 5 women (sex ratio 1). The average age of our patients was 47.4 years. In all cases radiological examinations showed proximally located nodular tumor ranging in size from 1 to 5.8 cm. Histological examination objectified mucoepidermoid carcinoma (6 out of 10 cases). All patients had localized or locally advanced tumors, with the exception of one case of metastatic mucoepidermoid carcinoma. Pulmonary salivary gland-type tumors correspond to a heterogeneous group of tumours. They are not very aggressive but are associated with a high frequency of recurrences and late metastases, requiring long-term monitoring.
摘要：
原发性肺涎腺型肿瘤罕见，具有特定的临床病理表现。它们是影响年轻受试者的近端肿瘤，与吸烟无关。为了优化管理，将它们与其他支气管肺肿瘤区分开来很重要，他们不分享生物学或治疗和结果。我们进行了一项回顾性研究,包括所有原发性恶性涎腺型肺部肿瘤，在32年的时间里，从1987年1月到2019年12月。我们从10名患者的医疗记录中收集了数据：5名男性和5名女性（性别比为1）。我们患者的平均年龄为47.4岁。在所有情况下，放射学检查均显示位于近端的结节状肿瘤，大小为1至5.8cm。组织学检查客观化的粘液表皮样癌（10例中有6例）。所有患者均有局部或局部晚期肿瘤，除了一例转移性粘液表皮样癌。肺涎腺型肿瘤对应于一组异质性肿瘤。它们不是非常积极，但与高频率的复发和晚期转移有关。需要长期监测。
