Abstract：
Access of sensory information to consciousness has been linked to the ignition of content-specific representations in association cortices. How does ignition interact with intrinsic cortical state fluctuations to give rise to conscious perception? We addressed this question in the prefrontal cortex (PFC) by combining multi-electrode recordings with a binocular rivalry (BR) paradigm inducing spontaneously driven changes in the content of consciousness, inferred from the reflexive optokinetic nystagmus (OKN) pattern. We find that fluctuations between low-frequency (LF, 1-9 Hz) and beta (∼20-40 Hz) local field potentials (LFPs) reflect competition between spontaneous updates and stability of conscious contents, respectively. Both LF and beta events were locally modulated. The phase of the former locked differentially to the competing populations just before a spontaneous transition while the latter synchronized the neuronal ensemble coding the consciously perceived content. These results suggest that prefrontal state fluctuations gate conscious perception by mediating internal states that facilitate perceptual update and stability.
摘要：
感觉信息对意识的访问已与关联皮层中特定内容的表示的点燃有关。点火如何与内在皮层状态波动相互作用以引起有意识的感知？我们通过将多电极记录与双目竞争（BR）范式相结合，在前额叶皮层（PFC）中解决了这个问题，从反射性视动性眼球震颤（OKN）模式推断。我们发现低频之间的波动(LF，1-9Hz）和β（〜20-40Hz）局部场电位（LFP）反映了自发更新和有意识内容稳定性之间的竞争，分别。LF和β事件均被局部调节。前者的阶段在自发过渡之前就不同地锁定到竞争人群，而后者同步了对有意识感知内容进行编码的神经元集合。这些结果表明，前额叶状态波动通过调节促进感知更新和稳定性的内部状态来控制意识感知。
