Abstract：
Word-centred neglect dyslexia is most commonly characterised as consequence of visuospatial neglect rather than an independent condition. However, recent research has suggested that this deficit may be dissociable from spatial attentional biases. This study aims to provide preliminary evidence investigating alternative mechanisms which could account for cases of word-centred neglect dyslexia which cannot be explained by visuospatial neglect. Patient EF is a chronic stroke survivor who presented with clear right-lateralised word-centred neglect dyslexia in conjunction with severe left egocentric neglect and left hemianopia following a right PCA stroke. The severity of EF\'s neglect dyslexia was not found to be affected by factors which modulate the severity of visuospatial neglect. EF demonstrated an intact ability to identify all letters in words, but reliably committed neglect dyslexia errors when subsequently reading the same words as a whole. EF did not exhibit neglect dyslexic impairment in standardised spelling, word-meaning matching, and word-picture matching tasks. Critically, EF exhibited marked cognitive inhibition impairment and committed neglect dyslexia errors which were characterised by misreading less familiar target words as more familiar responses. This behavioural pattern cannot be clearly accounted for by theories which characterize word-centred neglect dyslexia as a consequence of neglect. Instead, this data suggests that this case of word-centred neglect dyslexia may be related to a deficit of cognitive inhibition. Overall, these novel findings call for reevaluation of the dominant model of word-centred neglect dyslexia.
摘要：
以单词为中心的忽视阅读障碍最常见的特征是视觉空间忽视而不是独立条件。然而,最近的研究表明，这种缺陷可能与空间注意力偏差无关。这项研究旨在提供初步证据，以调查替代机制，这些机制可以解释无法通过视觉空间忽视来解释的以单词为中心的忽视阅读障碍的情况。患者EF是慢性中风幸存者，在右PCA中风后出现明显的以右侧为中心的以单词为中心的忽视阅读障碍，并伴有严重的左自我中心忽视和左偏盲。未发现EF的忽视阅读障碍的严重程度受调节视觉空间忽视严重程度的因素的影响。EF表现出完整的识别单词中所有字母的能力，但可靠地承诺忽视阅读障碍错误，当随后阅读相同的单词作为一个整体。EF在标准化拼写中没有表现出忽视阅读障碍，词义匹配,和单词图片匹配任务。严重的,EF表现出明显的认知抑制障碍和严重的忽视阅读障碍错误，其特征是将较不熟悉的目标单词误读为更熟悉的反应。这种行为模式不能被理论清楚地解释，这些理论将以单词为中心的忽视阅读障碍描述为忽视的结果。相反，这些数据表明，这种以单词为中心的忽视阅读障碍可能与认知抑制缺陷有关。总的来说,这些新发现要求重新评估以单词为中心的忽视阅读障碍的主导模式。
