Abstract：
Cuffless wearable devices are currently being developed for long-term monitoring of blood pressure (BP) in patients with hypertension and in apparently healthy people. This study evaluated the feasibility and measurement stability of smartwatch-based cuffless BP monitoring in real-world conditions. Users of the first smartwatch-based cuffless BP monitor approved in Korea (Samsung Galaxy Watch) were invited to upload their data from using the device for 4 weeks post calibration. A total of 760 participants (mean age 43.7 ± 11.9, 80.3% men) provided 35,797 BP readings (average monitoring 22 ± 4 days [SD]; average readings 47 ± 42 per participant [median 36]). Each participant obtained 1.5 ± 1.3 readings/day and 19.7% of the participants obtained measurements every day. BP showed considerable variability, mainly depending on the day and time of the measurement. There was a trend towards higher BP levels on Mondays than on other days of the week and on workdays than in weekends. BP readings taken between 00:00 and 04:00 tended to be the lowest, whereas those between 12:00 and 16:00 the highest. The average pre-post calibration error for systolic BP (difference in 7-day BP before and after calibration), was 6.8 ± 5.6 mmHg, and was increased with higher systolic BP levels before calibration. Smartwatch-based cuffless BP monitoring is feasible for out-of-office monitoring in the real-world setting. The stability of BP measurement post calibration and the standardization and optimal time interval for recalibration need further investigation.
摘要：
目前正在开发无袖口可穿戴设备，用于长期监测高血压患者和明显健康的人群的血压（BP）。这项研究评估了在现实条件下基于智能手表的无袖带BP监测的可行性和测量稳定性。韩国批准的第一款基于智能手表的无袖口BP显示器（三星GalaxyWatch）的用户被邀请在校准后4周内使用该设备上传其数据。总共760名参与者（平均年龄43.7±11.9，男性80.3％）提供了35,797个BP读数（平均监测22±4天[SD]；每个参与者的平均读数47±42[中位数36]）。每个参与者每天获得1.5±1.3的读数，每天有19.7％的参与者获得测量值。BP表现出相当大的变异性，主要取决于测量的日期和时间。周一的BP水平有高于一周中其他几天的趋势，工作日的BP水平有高于周末的趋势。00:00到04:00之间的血压读数往往是最低的，而12:00到16:00之间的是最高的。收缩压的校准前后平均误差（校准前后7天血压的差异），为6.8±5.6mmHg，并且在校准前随着较高的收缩压水平而增加。基于Smartwatch的无袖口BP监控在现实环境中的外出监控是可行的。校准后BP测量的稳定性以及重新校准的标准化和最佳时间间隔需要进一步研究。
