Abstract：
OBJECTIVE: To assess whether having a pet in the home is a risk factor for community-acquired urinary tract infections associated with extended-spectrum β-lactamase (ESBL)- or AmpC β-lactamase (ACBL)- producing Enterobacterales.
METHODS: An unmatched case-control study was conducted between August 2015 and September 2017. Cases (n = 141) were people with community-acquired urinary tract infection (UTI) caused by ESBL- or ACBL-producing Enterobacterales. Controls (n = 525) were recruited from the community. A telephone questionnaire on pet ownership and other factors was administered, and associations were assessed using logistic regression.
RESULTS: Pet ownership was not associated with ESBL- or ACBL-producing Enterobacterales-related human UTIs. A positive association was observed for recent antimicrobial treatment, travel to Asia in the previous year, and a doctor\'s visit in the last 6 months. Among isolates with an ESBL-/ACBL-producing phenotype, 126/134 (94%) were Escherichia coli, with sequence type 131 being the most common (47/126).
CONCLUSIONS: Companion animals in the home were not found to be associated with ESBL- or ACBL-producing Enterobacterales-related community-acquired UTIs in New Zealand. Risk factors included overseas travel, recent antibiotic use, and doctor visits.
METHODS: An unmatched case-control study was conducted between August 2015 and September 2017. Cases (n = 141) were people with community-acquired urinary tract infection (UTI) caused by ESBL- or ACBL-producing Enterobacterales. Controls (n = 525) were recruited from the community. A telephone questionnaire on pet ownership and other factors was administered, and associations were assessed using logistic regression.
RESULTS: Pet ownership was not associated with ESBL- or ACBL-producing Enterobacterales-related human UTIs. A positive association was observed for recent antimicrobial treatment, travel to Asia in the previous year, and a doctor\'s visit in the last 6 months. Among isolates with an ESBL-/ACBL-producing phenotype, 126/134 (94%) were Escherichia coli, with sequence type 131 being the most common (47/126).
CONCLUSIONS: Companion animals in the home were not found to be associated with ESBL- or ACBL-producing Enterobacterales-related community-acquired UTIs in New Zealand. Risk factors included overseas travel, recent antibiotic use, and doctor visits.
摘要：
目的：评估在家中养宠物是否是与产超广谱β-内酰胺酶（ESBL）或AmpCβ-内酰胺酶（ACBL）相关的社区获得性尿路感染的危险因素。
方法：2015年8月至2017年9月进行了一项无匹配的病例对照研究。病例（n=141）是由产生ESBL或ACBL的肠杆菌引起的社区获得性尿路感染（UTI）。从社区招募对照(n=525)。关于宠物所有权的电话问卷，和其他因素进行管理，和关联使用逻辑回归进行评估。
结果：宠物所有权与产生ESBL或ACBL的肠杆菌相关人类UTI无关。观察到近期抗菌治疗呈正相关，前一年去亚洲旅行，和医生在过去六个月的访问。在具有产ESBL/ACBL表型的分离株中，126/134（94％）是大肠杆菌，序列类型（ST）131是最常见的（47/126）。
结论：在新西兰，未发现家庭中的伴侣动物与产生ESBL或ACBL的肠杆菌相关的社区获得性UTI相关。风险因素包括海外旅行，最近使用抗生素，和医生访问。
方法：2015年8月至2017年9月进行了一项无匹配的病例对照研究。病例（n=141）是由产生ESBL或ACBL的肠杆菌引起的社区获得性尿路感染（UTI）。从社区招募对照(n=525)。关于宠物所有权的电话问卷，和其他因素进行管理，和关联使用逻辑回归进行评估。
结果：宠物所有权与产生ESBL或ACBL的肠杆菌相关人类UTI无关。观察到近期抗菌治疗呈正相关，前一年去亚洲旅行，和医生在过去六个月的访问。在具有产ESBL/ACBL表型的分离株中，126/134（94％）是大肠杆菌，序列类型（ST）131是最常见的（47/126）。
结论：在新西兰，未发现家庭中的伴侣动物与产生ESBL或ACBL的肠杆菌相关的社区获得性UTI相关。风险因素包括海外旅行，最近使用抗生素，和医生访问。
