{Reference Type}: Journal Article
{Title}: Extended-spectrum β-lactamase- and AmpC β-lactamase-producing Enterobacterales associated with urinary tract infections in the New Zealand community: a case-control study.
{Author}: Toombs-Ruane LJ;Marshall JC;Benschop J;Drinković D;Midwinter AC;Biggs PJ;Grange Z;Baker MG;Douwes J;Roberts MG;French NP;Burgess SA;
{Journal}: Int J Infect Dis
{Volume}: 128
{Issue}: 0
{Year}: Mar 2023
{Factor}: 12.074
{DOI}: 10.1016/j.ijid.2022.12.013
{Abstract}: <B>OBJECTIVE: </B>To assess whether having a pet in the home is a risk factor for community-acquired urinary tract infections associated with extended-spectrum β-lactamase (ESBL)- or AmpC β-lactamase (ACBL)- producing Enterobacterales.<BR><B>METHODS: </B>An unmatched case-control study was conducted between August 2015 and September 2017. Cases (n = 141) were people with community-acquired urinary tract infection (UTI) caused by ESBL- or ACBL-producing Enterobacterales. Controls (n = 525) were recruited from the community. A telephone questionnaire on pet ownership and other factors was administered, and associations were assessed using logistic regression.<BR><B>RESULTS: </B>Pet ownership was not associated with ESBL- or ACBL-producing Enterobacterales-related human UTIs. A positive association was observed for recent antimicrobial treatment, travel to Asia in the previous year, and a doctor's visit in the last 6 months. Among isolates with an ESBL-/ACBL-producing phenotype, 126/134 (94%) were Escherichia coli, with sequence type 131 being the most common (47/126).<BR><B>CONCLUSIONS: </B>Companion animals in the home were not found to be associated with ESBL- or ACBL-producing Enterobacterales-related community-acquired UTIs in New Zealand. Risk factors included overseas travel, recent antibiotic use, and doctor visits.