Abstract:
Radiation therapy (RT) is a key component of the management of elderly breast cancer patients. However, level I evidence in elderly patients is limited. Patient selection should include comorbidities and geriatric assessment. Advances in radiation planning and delivery are improving target coverage, reducing toxicity, and expanding treatment eligibility. Some alternative techniques, such as treatment in the lateral or prone position, may reduce the risk of toxicity. Shorter cycles of hypofractionated whole breast RT are safe and effective. In some cases, partial breast irradiation may be an option.
摘要:
放射治疗(RT)是老年乳腺癌患者管理的关键组成部分。然而,老年患者的I级证据有限。患者选择应包括合并症和老年评估。辐射规划和交付方面的进展正在提高目标覆盖率,减少毒性,扩大治疗资格。一些替代技术,如侧卧位或俯卧位治疗,可以降低毒性的风险。低分割全乳房RT的较短周期是安全有效的。在某些情况下,部分乳房照射可能是一种选择。