UNASSIGNED: the findings obtained from clinical trials and systematic reviews highlight that most patients with COVID-19 have decreased vitamin D levels and low levels of vitamin D increase the risk of severe disease. This evidence seems to be also confirmed in the pediatric population.
UNASSIGNED: further studies (systematic review and meta-analysis) conducted on children are needed to confirm that vitamin D affects COVID-19 outcomes and to determine the effectiveness of supplementation and the appropriate dose, duration and mode of administration.
UNASSIGNED:从临床试验和系统评价中获得的发现强调,大多数COVID-19患者的维生素D水平降低,维生素D水平低增加了严重疾病的风险。这一证据似乎也在儿科人群中得到证实。
UNASSIGNED:需要对儿童进行进一步的研究(系统评价和荟萃分析),以确认维生素D会影响COVID-19的结局,并确定补充剂的有效性和适当的剂量,持续时间和给药方式。