{Reference Type}: Journal Article {Title}: Vitamin D status can affect COVID-19 outcomes also in pediatric population. {Author}: Miraglia Del Giudice M;Indolfi C;Dinardo G;Decimo F;Decimo A;Klain A; {Journal}: PharmaNutrition {Volume}: 22 {Issue}: 0 {Year}: Dec 2022 暂无{DOI}: 10.1016/j.phanu.2022.100319 {Abstract}: UNASSIGNED: vitamin D influences the immune system and the inflammatory response. It is known that vitamin D supplementation reduces the risk of acute respiratory tract infection. In the last two years, many researchers have investigated vitamin D's role in the pathophysiology of COVID-19 disease.
UNASSIGNED: the findings obtained from clinical trials and systematic reviews highlight that most patients with COVID-19 have decreased vitamin D levels and low levels of vitamin D increase the risk of severe disease. This evidence seems to be also confirmed in the pediatric population.
UNASSIGNED: further studies (systematic review and meta-analysis) conducted on children are needed to confirm that vitamin D affects COVID-19 outcomes and to determine the effectiveness of supplementation and the appropriate dose, duration and mode of administration.