%0 Journal Article
%T Vitamin D status can affect COVID-19 outcomes also in pediatric population.
%A Miraglia Del Giudice M
%A Indolfi C
%A Dinardo G
%A Decimo F
%A Decimo A
%A Klain A
%J PharmaNutrition
%V 22
%N 0
%D Dec 2022
%M 36268528
暂无%R 10.1016/j.phanu.2022.100319
%X <B>UNASSIGNED: </B>vitamin D influences the immune system and the inflammatory response. It is known that vitamin D supplementation reduces the risk of acute respiratory tract infection. In the last two years, many researchers have investigated vitamin D's role in the pathophysiology of COVID-19 disease.<BR><B>UNASSIGNED: </B>the findings obtained from clinical trials and systematic reviews highlight that most patients with COVID-19 have decreased vitamin D levels and low levels of vitamin D increase the risk of severe disease. This evidence seems to be also confirmed in the pediatric population.<BR><B>UNASSIGNED: </B>further studies (systematic review and meta-analysis) conducted on children are needed to confirm that vitamin D affects COVID-19 outcomes and to determine the effectiveness of supplementation and the appropriate dose, duration and mode of administration.