Abstract：
The pandemic due to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has emerged as a serious global public health issue. Besides the high transmission rate from individual to individual, indirect transmission from inanimate objects or surfaces poses a more significant threat. Since the start of the outbreak, the importance of respiratory protection, social distancing, and chemical disinfection to prevent the spread of the virus has been the prime focus for infection control. Health regulatory organizations have produced guidelines for the formulation and application of chemical disinfectants to manufacturing industries and the public. On the other hand, extensive literature on the virucidal efficacy testing of microbicides for SARS-CoV-2 has been published over the past year and a half. This review summarizes the studies on the most common chemical disinfectants and their virucidal efficacy against SARS-CoV-2, including the type and concentration of the chemical disinfectant, the formulation, the presence of excipients, the exposure time, and other critical factors that determine the effectiveness of chemical disinfectants. In this review, we also critically appraise these disinfectants and conduct a discussion on the role they can play in the COVID-19 pandemic.
摘要：
严重急性呼吸系统综合症冠状病毒2（SARS-CoV-2）引起的大流行已成为严重的全球公共卫生问题。除了从个人到个人的高传输速率，来自无生命物体或表面的间接传播构成了更大的威胁。自疫情爆发以来,呼吸保护的重要性，社交距离，防止病毒传播的化学消毒一直是感染控制的首要重点。卫生监管组织已经制定了化学消毒剂的配制和应用指南，用于制造业和公众。另一方面,在过去的一年半中，已经发表了有关SARS-CoV-2的杀微生物剂的杀病毒功效测试的大量文献。本文综述了最常见的化学消毒剂及其对SARS-CoV-2的杀病毒功效的研究，包括化学消毒剂的类型和浓度，配方，赋形剂的存在，曝光时间,以及其他决定化学消毒剂有效性的关键因素。在这次审查中,我们还严格评估了这些消毒剂，并就它们在COVID-19大流行中的作用进行了讨论。
