关键词: ABTS, 2,2′-Azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) AKP, Alkaline phosphatase ALT, Alanine aminotransferase AST, Asparate aminotransferase Ara, Arabinose BUN, Blood urea nitrogen Bax, Bcl2-associated X protein Bcl-2, B-cell lymphoma Biological activities CCl4, Carbon tetrachloride COX-2, Cyclooxygenase-2 Caspase-3, Cysteinyl aspartate specific proteinase 3 Caspase-9, Cysteinyl aspartate specific proteinase 9 DPPH, 2.2-diphenyl-picryl-hydrazyl radical EAE, Enzyme-assisted extraction FRAP, Ferric ion reducing antioxidant power FTIR, Fourier transform infrared spectroscopy Future trends GC, Gas chromatography GC–MS, Gas chromatography-mass spectrometry GSH-Px, Glutathione peroxidase Gal, Galactose Glc, Glucose HDL, High-density Lipoprotein HPGPC, High-performance gel permeation chromatography HPLC, High performance liquid chromatography HepG2, Human hepatocellular carcinoma cell line IL-10, Interleukin-10 IL-1β, Interleukin 1β IL-2, Interleukin-2 IL-6, Interleukin-6 LDL, Low-density Lipoprotein LPS, Lipopolysaccharide M. oleifera Lam, Moringa oleifera Lam. MAE, Microwave-assisted extraction MDA, Malondialdehyde MOPs, Moringa oleifera Lam polysaccharides MS, Mass spectrometry MTT, 3‐(4,5‐dimethylthiazol‐2‐yl)‐2,5‐diphenyl tetrazolium bromide MW, Molecular weight Man, Mannose Moringa oleifera Lam NF-κB, Nuclear factor kappa-B NK, Natural killer cell NMR, Nuclear magnetic resonance NO, Nitric oxide PLE, Pressurized liquid extraction Polysaccharides ROS, Reactive oxygen species Rha, Rhamnose SCFAs, Short-chain fatty acids SOD, Superoxide dismutase Structure characteristics Structure-biological relationship TC, Total Cholesterol TG, Triglycerides TNF-α, Tumour necrosis factor-α TOF, Time of flight UAE, Ultrasound-assisted extraction V/C, Ileum crypt and villus length WAE, Water-assisted extraction Xyl, Xylose iNOS, Inducible nitric oxide synthase

来  源:   DOI:10.1016/j.fochx.2022.100322   PDF(Pubmed)

Abstract:
Moringa oleifera Lam. (M. oleifera Lam) is a perennial tropical deciduous tree that belongs to the Moringaceae family. Polysaccharides are one of the major bioactive compounds in M. oleifera Lam and show immunomodulatory, anticancer, antioxidant, intestinal health protection and antidiabetic activities. At present, the structure and functional activities of M. oleifera Lam polysaccharides (MOPs) have been widespread, but the research data are relatively scattered. Moreover, the relationship between the structure and biological activities of MOPs has not been summarized. In this review, the current research on the extraction, purification, structural characteristics and biological activities of polysaccharides from different sources of M. oleifera Lam were summarized, and the structural characteristics of purified polysaccharides were focused on this review. Meanwhile, the biological activities of MOPs were introduced, and some molecular mechanisms were listed. In addition, the relationship between the structure and biological activities of MOPs was discussed. Furthermore, new perspectives and some future research of M. oleifera Lam polysaccharides were proposed in this review.
摘要:
辣木。(M.oleiferaLam)是一种多年生的热带落叶树,属于辣根科。多糖是油茶中主要的生物活性化合物之一,抗癌,抗氧化剂,肠道健康保护和抗糖尿病活性。目前,油茶多糖(MOPs)的结构和功能活性得到了广泛的研究,但是研究数据相对分散。此外,MOPs的结构与生物活性之间的关系尚未总结。在这次审查中,目前对提取的研究,净化,综述了不同来源油茶多糖的结构特征和生物活性,本文对纯化多糖的结构特征进行了综述。同时,介绍了MOPs的生物活性,并列举了一些分子机制。此外,讨论了MOPs的结构与生物活性之间的关系。此外,本文对油茶多糖的研究提出了新的观点和未来的研究方向。
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