Abstract：
The effect of a vegetarian diet on bone health remains controversial. This retrospective medical record review compared changes in bone mineral density (BMD) and trabecular bone score (TBS) between vegetarian and non-vegetarian middle-aged and older women who underwent two general health examinations (T1 and T2) that were approximately three years apart. Generalized estimating equations were used to compare the change in lumbar spine and bilateral hip BMD and TBS over time. At T1, the mean age of the patients was 56.6 years (standard deviation 9.7 years) and the mean interval between T1 and T2 was 2.7 years. For women aged 40-55 years, compared with non-vegetarians, vegetarians were significantly associated with a larger reduction in lumbar spine BMD (p < 0.001) and left hip femoral neck BMD (p = 0.015) over the three-year interval. On the contrary, changes in BMD were not significant at any site in women aged ≥ 56 years. Moreover, the changes in BMD and TBS over the three-year interval did not significantly differ between vegetarian and non-vegetarian women aged 65-90 years. In conclusion, for women aged 40-55 years, vegetarian diets reduced bone quantity, as measured by BMD, but not bone quality, as measured by TBS.
摘要：
素食对骨骼健康的影响仍然存在争议。这项回顾性医疗记录审查比较了素食和非素食中年和老年女性之间的骨矿物质密度（BMD）和骨小梁评分（TBS）的变化，这些女性接受了大约三年的两次一般健康检查（T1和T2）。使用广义估计方程比较腰椎和双侧髋部BMD和TBS随时间的变化。T1时，患者的平均年龄为56.6岁（标准偏差9.7岁），T1和T2之间的平均间隔为2.7年。对于40-55岁的女性，与非素食者相比，在三年的时间间隔内，素食者与腰椎BMD（p<0.001）和左髋股骨颈BMD（p=0.015）的降低显着相关。相反,年龄≥56岁女性的任何部位的BMD变化均不显著.此外，年龄在65~90岁的素食和非素食女性之间,3年间隔内BMD和TBS的变化没有显著差异.总之,对于40-55岁的女性，素食减少骨骼数量，以BMD测量，但不是骨骼质量，由TBS测量。
