METHODS: Enrolled literature was identified through PubMed, EMBASE, and BIOSIS. An additional manual search of old reports before the introduction of efficient modern therapies, which can interfere with the spontaneous disease, was performed.
RESULTS: Thirteen studies were enrolled. About 50% of psoriasis patients were stable and showed no seasonal difference between seasons. Approximately 30% improved in summer, and 20% performed better in winter, some with marked summer worsening. European results matched international reports from different continents and hemispheres with climate extremes. The psychological effects could not be ruled out.
CONCLUSIONS: About 50% of psoriasis patients experience a season-independent disease, however, with a subset of patients who do better in summer. Others again do better in winter, with a few of these having marked worsening in warm periods. Individual season-related activity records should be paid proper attention to when considering light therapy or climatotherapy as a treatment.
方法:注册文献是通过PubMed,EMBASE,和生物。在引入有效的现代疗法之前,对旧报告进行额外的手动搜索,会干扰自发性疾病,已执行。
结果:共纳入13项研究。约50%的银屑病患者病情稳定,季节间无季节差异。夏季改善了约30%,20%的人在冬天表现更好,有些夏天明显恶化。欧洲的结果与来自不同大陆和半球的极端气候的国际报告相匹配。不能排除心理影响。
结论:约50%的银屑病患者经历了与季节无关的疾病,然而,有一部分病人在夏天做得更好。其他人在冬天又做得更好,其中一些在温暖时期明显恶化。在考虑光疗或气候疗法作为治疗方法时,应适当注意与季节有关的个人活动记录。