PDF(Pubmed)
Abstract：
Radiation therapy is a cornerstone of cancer therapy, with >50% of patients undergoing therapeutic radiation. As a result of widespread use and improved survival, there is increasing focus on the potential long-term effects of ionizing radiation, especially cardiovascular toxicity. Radiation therapy can lead to atherosclerosis of the vasculature as well as valvular, myocardial, and pericardial dysfunction. We present a consensus statement from the International Cardio-Oncology Society based on general principles of radiotherapy delivery and cardiovascular risk assessment and risk mitigation in this population. Anatomical-based recommendations for cardiovascular management and follow-up are provided, and a priority is given to the early detection of atherosclerotic vascular disease on imaging to help guide preventive therapy. Unique management considerations in radiation-induced cardiovascular disease are also discussed. Recommendations are based on the most current literature and represent a unanimous consensus by the multidisciplinary expert panel.
摘要：
放射治疗是癌症治疗的基石,>50%的患者接受放射治疗。由于广泛使用和改善生存，人们越来越关注电离辐射的潜在长期影响，尤其是心血管毒性.放射治疗可导致血管和瓣膜的动脉粥样硬化，心肌,和心包功能障碍。我们提出了国际心血管肿瘤学会的共识声明，该声明基于该人群的放射治疗和心血管风险评估以及风险缓解的一般原则。提供了基于解剖学的心血管管理和随访建议，并优先考虑在影像学上早期发现动脉粥样硬化性血管疾病，以帮助指导预防治疗。还讨论了辐射诱发的心血管疾病的独特管理考虑因素。建议基于最新文献，代表了多学科专家小组的一致共识。
