关键词: AD, Alzheimer's disease ALS, amyotrophic lateral sclerosis AMPK, 5′-adenosine monophosphate-activated protein kinase ATF6, activating transcription factor 6 ATG, autophagy related genes Autophagy BCL-2, B-cell lymphoma 2 BNIP3L, BCL2/adenovirus COPII, coat protein complex II Cerebral ischemia ER, endoplasmic reticulum FOXO, forkhead box O FUNDC1, FUN14 domain containing 1 GPCR, G-protein coupled receptor HD, Huntington's disease IPC, ischemic preconditioning IRE1, inositol-requiring enzyme 1 JNK, c-Jun N-terminal kinase LAMP, lysosomal-associated membrane protein LC3, light chain 3 LKB1, liver kinase B1 Lysosomal activation Mitochondria Mitophagy Natural compounds Neurological disorders Neuroprotection OGD/R, oxygen and glucose deprivation-reperfusion PD, Parkinson's disease PERK, protein kinase R (PKR)-like endoplasmic reticulum kinase PI3K, phosphatidylinositol 3-kinase ROS, reactive oxygen species SQSTM1, sequestosome 1 TFEB, transcription factor EB TIGAR, TP53-induced glycolysis and apoptosis regulator ULK, Unc-51- like kinase Uro-A, urolithin A eIF2a, eukaryotic translation-initiation factor 2 mTOR, mechanistic target of rapamycin ΔΨm, mitochondrial membrane potential
来 源:
DOI:10.1016/j.apsb.2020.10.018
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