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Abstract：
The crucial role of the immune system in the progression/regression of breast cancer (BC) should always be taken into account. Various immunotherapy approaches have been investigated for BC, including tumor-targeting antibodies (bispecific antibodies), adoptive T cell therapy, vaccines, and immune checkpoint blockade such as anti-PD-1. In addition, a combination of conventional chemotherapy and immunotherapy approaches contributes to improving patients\' overall survival rates. Although encouraging outcomes have been reported in most clinical trials of immunotherapy, some obstacles should still be resolved in this regard. Recently, personalized immunotherapy has been proposed as a potential complementary medicine with immunotherapy and chemotherapy for overcoming BC. Accordingly, this review discusses the brief association of these methods and future directions in BC immunotherapy.
摘要：
应始终考虑免疫系统在乳腺癌（BC）进展/消退中的关键作用。已经对BC进行了各种免疫治疗方法的研究，包括肿瘤靶向抗体（双特异性抗体），过继性T细胞疗法,疫苗,和免疫检查点阻断如抗PD-1。此外,常规化疗和免疫治疗相结合有助于提高患者的总体生存率.尽管在大多数免疫治疗的临床试验中已经报道了令人鼓舞的结果，在这方面仍然应该解决一些障碍。最近,个性化免疫疗法已被提出作为克服BC的免疫疗法和化学疗法的潜在补充药物。因此，这篇综述讨论了这些方法的简要关联以及BC免疫治疗的未来方向.
