关键词: FnCas12a PAM RS1 activity variant
Mesh : Bacterial Proteins / genetics metabolism CRISPR-Associated Proteins / genetics metabolism CRISPR-Cas Systems Cells, Cultured Endodeoxyribonucleases / genetics metabolism Evolution, Molecular Eye Proteins / genetics Francisella / enzymology genetics isolation & purification Gene Editing / methods Humans Mutation Protein Engineering / methods Retinoschisis / genetics metabolism pathology Selection, Genetic Structure-Activity Relationship
来 源:
DOI:10.1016/j.jbc.2021.100394
PDF(Sci-hub)
PDF(Pubmed)