关键词: Alzheimer's disease Metabolomic Mitophagy N2a/APP695swe cells Valinomycin
Mesh : Adenosine Triphosphate / biosynthesis Alzheimer Disease / genetics metabolism pathology Amyloid beta-Peptides / genetics metabolism Amyloid beta-Protein Precursor / genetics metabolism pharmacology Animals Cell Line, Tumor Gene Expression Regulation Humans Ionophores / pharmacology Membrane Potential, Mitochondrial / drug effects Membrane Transport Proteins / genetics metabolism Metabolomics / methods Mice Microtubule-Associated Proteins / genetics metabolism Mitochondria / drug effects metabolism pathology Mitochondrial Precursor Protein Import Complex Proteins Mitophagy / drug effects genetics Models, Biological Neurons / drug effects metabolism pathology Peptide Fragments / genetics metabolism Protein Kinases / genetics metabolism Receptors, Cell Surface / genetics metabolism Ubiquitin-Protein Ligases / genetics metabolism Valinomycin / pharmacology
来 源:
DOI:10.1016/j.yexcr.2020.112266
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