PDF(Pubmed)
Abstract：
Blood flow-restricted exercise (BFRE) appears to hold considerable potential in spinal cord injury (SCI) rehabilitation, due to its ability to induce beneficial functional changes and morphological alterations from low-intensity, low-load exercise. However, it remains unclear if this training approach is feasible and safe in individuals with autonomic dysreflexia (AD).
A 23-year-old male with traumatic, cervical (C6), motor-complete (AIS: B) SCI and diagnosed AD completed eight sessions of BFRE for the upper extremities over 4 weeks. Blood pressure and heart rate recordings and perceptual pain responses were collected repeatedly during exercise. Blood samples were drawn pre- and post-training. Training was carried out in a neurorehabilitation hospital setting with appertaining medical staff readiness, and was supervised by a physiotherapist with expertise in AD in general as well as prior knowledge of the present patient\'s triggers and symptoms. Four incidences of AD (defined as systolic blood pressure increase >20 mmHg) were recorded across all training sessions, of which one was symptomatic. The patient\'s blood profile did not change considerably from pre- to post-training sessions. Self-reported average pain during training corresponded from \"mild\" to \"moderate\".
The patient was able to perform 4 weeks of BFRE, but encountered episodes of AD. Similarly, two AD episodes were registered during a single conventional, free-flow resistance training session. Evidence from clinically controlled safety studies is needed in order to establish if and how BFRE can be applied in a rehabilitation strategy in SCI individuals with neurological level of injury at or above T6 level.
A 23-year-old male with traumatic, cervical (C6), motor-complete (AIS: B) SCI and diagnosed AD completed eight sessions of BFRE for the upper extremities over 4 weeks. Blood pressure and heart rate recordings and perceptual pain responses were collected repeatedly during exercise. Blood samples were drawn pre- and post-training. Training was carried out in a neurorehabilitation hospital setting with appertaining medical staff readiness, and was supervised by a physiotherapist with expertise in AD in general as well as prior knowledge of the present patient\'s triggers and symptoms. Four incidences of AD (defined as systolic blood pressure increase >20 mmHg) were recorded across all training sessions, of which one was symptomatic. The patient\'s blood profile did not change considerably from pre- to post-training sessions. Self-reported average pain during training corresponded from \"mild\" to \"moderate\".
The patient was able to perform 4 weeks of BFRE, but encountered episodes of AD. Similarly, two AD episodes were registered during a single conventional, free-flow resistance training session. Evidence from clinically controlled safety studies is needed in order to establish if and how BFRE can be applied in a rehabilitation strategy in SCI individuals with neurological level of injury at or above T6 level.
摘要：
血流受限运动（BFRE）似乎在脊髓损伤（SCI）康复中具有相当大的潜力，由于其从低强度诱导有益的功能变化和形态改变的能力，低负荷运动。然而,目前尚不清楚这种训练方法在自主神经反射异常(AD)患者中是否可行和安全.
一名23岁的男性遭受创伤,子宫颈（C6），运动完全（AIS：B）SCI和诊断的AD在4周内完成了8次上肢BFRE治疗。在运动过程中反复收集血压和心率记录以及感知疼痛反应。在训练前和训练后抽取血样。培训是在神经康复医院的环境中进行的，有相应的医务人员准备，并由具有一般AD专业知识以及对当前患者的诱因和症状的先验知识的物理治疗师监督。在所有训练课程中记录四次AD发生率（定义为收缩压升高>20mmHg）。其中一个是有症状的。从训练前到训练后，患者的血液状况没有明显变化。训练期间自我报告的平均疼痛从“轻度”到“中度”。
患者能够进行4周的BFRE，但遇到了AD的情节。同样，在一次常规的AD发作中记录了两次，自由流动阻力训练课程。需要来自临床对照安全性研究的证据，以确定是否以及如何将BFRE应用于具有T6水平或以上神经损伤水平的SCI个体的康复策略。
一名23岁的男性遭受创伤,子宫颈（C6），运动完全（AIS：B）SCI和诊断的AD在4周内完成了8次上肢BFRE治疗。在运动过程中反复收集血压和心率记录以及感知疼痛反应。在训练前和训练后抽取血样。培训是在神经康复医院的环境中进行的，有相应的医务人员准备，并由具有一般AD专业知识以及对当前患者的诱因和症状的先验知识的物理治疗师监督。在所有训练课程中记录四次AD发生率（定义为收缩压升高>20mmHg）。其中一个是有症状的。从训练前到训练后，患者的血液状况没有明显变化。训练期间自我报告的平均疼痛从“轻度”到“中度”。
患者能够进行4周的BFRE，但遇到了AD的情节。同样，在一次常规的AD发作中记录了两次，自由流动阻力训练课程。需要来自临床对照安全性研究的证据，以确定是否以及如何将BFRE应用于具有T6水平或以上神经损伤水平的SCI个体的康复策略。
