靶向基因组测序在癌症研究中的应用与分析。
关键词: BAM, Binary Alignment Map BWA, Burrows-Wheeler Aligner Background error CLL, Chronic Lymphocytic Leukaemia COSMIC, Catalogue of Somatic Mutations in Cancer Cancer genomics Clinical samples ESP, Exome Sequencing Project FF, Fresh Frozen FFPE, Formalin Fixed Paraffin Embedded FL, Follicular Lymphoma GATK, Genome Analysis Toolkit ICGC, International Cancer Genome Consortium MBC, Molecular Barcode NCCN, the National Comprehensive Cancer Network® NGS, Next Generation Sequencing NHL, Non-Hodgkin Lymphoma NSCLC, Non-Small Cell Lung Carcinoma PCR duplicates QC, Quality Control SAM, Sequence Alignment Map TCGA, The Cancer Genome Atlas TS, Targeted Sequencing Targeted sequencing UMI, Unique Molecular Identifiers VAF, Variant Allele Frequency Variant calling WES, Whole Exome Sequencing WGS, Whole Genome Sequencing tFL, Transformed Follicular Lymphoma
来 源:
DOI:10.1016/j.csbj.2019.10.004
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